{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:06:48Z","timestamp":1785942408802,"version":"3.56.0"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T00:00:00Z","timestamp":1560988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Kaposi sarcoma (KS) age\u2010standardized incidence rate is below 0.3 per 100,000 in Nordic countries. Data on KS in Finland have been sparse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of all the patients with KS cases managed in the Helsinki University Central Hospital between 2006 and 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty patients (median age at diagnosis 45\u00a0years, 38 males) were included. About 2.5 new cases were diagnosed per year (incidence 0.16 \/100,000). The different subtypes of KS were: human immunodeficiency virus (HIV) (65%), classical KS (30%), and immunodepression (5%). Patients with HIV were significantly younger, more likely to have cutaneous lesions of the face, the trunk, and mucosal lesions,\u00a0and KS within\u00a0lymph nodes and inner organs. KS was diagnosed at the same time as HIV in 77% of cases, 28% with CD4\u2010cell level above 300\u00a0cells\/mm<jats:sup>3<\/jats:sup>. Among the patients with classical KS (<jats:italic>n<\/jats:italic>\u00a0=\u00a012), 75% were of Finnish origin, 41% had a second primary malignancy diagnosed, and 25% had noninsulin dependent diabetes mellitus. Among HIV patients, 27% had another AIDS\u2010related illness, 7% of the patients developed lymphoproliferative disorders, and 7% a hemophagocytic syndrome. Patients with HIV were always treated with antiviral therapy, with pegylated liposomal doxorubicin in 57% of the cases. Local radiotherapy was the main treatment for other KS types. None of the 5 deaths during follow\u2010up was related to KS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Classical KS (KS\u2010CLA) occurs among native Finns, frequently with other present malignancies. Screening of HIV and other malignancies is warranted in new cases of KS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14563","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T05:34:05Z","timestamp":1561095245000},"page":"1258-1263","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Kaposi sarcoma in Southern Finland (2006\u20132018)"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5225-8316","authenticated-orcid":false,"given":"Nicolas","family":"Kluger","sequence":"first","affiliation":[{"name":"Dermatology, Allergology and Venereology Helsinki University Central Hospital and University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Blomqvist","sequence":"additional","affiliation":[{"name":"Comprehensive Cancer Center Helsinki University Central Hospital and University of Helsinki 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