{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:32:24Z","timestamp":1789410744700,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T00:00:00Z","timestamp":1569110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitiligo is an acquired pigmentary disorder that affects approximately 0.5\u20132% of the world's population, and 25% of cases begin before 10\u00a0years of age. Although prevalent, there are few studies on the characterization of childhood vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the clinical and epidemiological characteristics of childhood vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Transverse study conducted by reviewing data records of patients under the age of 18 in which disease onset occurred before 13\u00a0years of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Predominance of females (62%). The most common subtype was generalized vitiligo (53.8%). The average age of disease onset was 5.9\u00a0years. The most affected initial site was head\/neck (44.22%). The Koebner phenomenon was present in 38.2%, emotional triggering factors in 67.0% of the patients, halo nevus in 17.4%, and associated autoimmune disease in 6.5% of the patients. Family history of vitiligo was observed in 16.9% of the patients, and stability was reported by 20.1% of patients. The presence of positive family history did not significantly influence the age of onset. We found a significant difference between segmental vitiligo (SV) and nonsegmental vitiligo (NSV) regarding the age of onset, Koebner phenomenon, hypothyroidism, anti\u2010TPO antibodies, family history of psoriasis, and halo nevus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Childhood vitiligo has its own characteristics. Vitiligo different subtypes have distinct characteristics. Our study presents a great number of patients, helping to elucidate the peculiarities of childhood vitiligo in the Brazilian population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.14645","type":"journal-article","created":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T06:38:21Z","timestamp":1569220701000},"page":"236-244","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Clinical and epidemiological characteristics of childhood vitiligo: a study of 701 patients from Brazil"],"prefix":"10.1111","volume":"59","author":[{"given":"Clarissa Pereira dos Santos","family":"Martins","sequence":"first","affiliation":[{"name":"Professor Rubem David Azulay Institute of Dermatology Vitiligo Clinic Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Hertz","sequence":"additional","affiliation":[{"name":"Professor Rubem David Azulay Institute of Dermatology Vitiligo Clinic 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