{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:20:33Z","timestamp":1790742033438,"version":"4.1.0"},"reference-count":69,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T00:00:00Z","timestamp":1571961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Hidradenitis suppurativa (HS) is a systemic recalcitrant inflammatory condition characterized by debilitating lesions with high morbidity. Its known association with obesity and smoking indicate correlation with other environmental factors, such as diet, suggesting a larger role for lifestyle modifications in disease treatment. This study seeks to assess the contribution of weight loss and dietary intake in HS management. A primary literature search was conducted using PubMed, Web of Science, and CINAHL in November 2018 to include association and intervention studies on the influence of diet and weight on HS. Twenty\u2010five articles were included. Meta\u2010analysis of nine case\u2013control studies across Asia, Europe, and the United States showed that HS patients are four times more likely to be obese compared to the general population; random effects pooled odds ratio 4.022 (2.667\u20136.065),\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001. Five articles assessed weight\u2010loss interventions and revealed mixed findings. The remaining articles included three association studies on micronutrient levels, eight dietary intervention studies, and one article analyzing both micronutrient association and dietary intervention. Included articles in this systematic review reveal that low serum zinc and vitamin D levels are associated with increased lesion count in HS. Supplementation of zinc, vitamin D, vitamin B12, or exclusion of dairy or brewer\u2019s yeast can be effective in partial or complete lesion resolution. Reviewed data show that weight loss from bariatric surgery may lead to HS improvement but often results in more severe malnutrition that worsens or even leads to new onset HS post bariatric surgery. Future reporting is needed to conclusively determine the role of diet in HS.\n                  <\/jats:p>","DOI":"10.1111\/ijd.14691","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T07:06:12Z","timestamp":1571987172000},"page":"143-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Dietary and metabolic factors in the pathogenesis of hidradenitis suppurativa: a systematic review"],"prefix":"10.1111","volume":"59","author":[{"given":"Franchesca","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California, Irvine Irvine CA USA"},{"name":"Kaohsiung Medical University School of Medicine Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa","family":"Lehmer","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Ekelem","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha A.","family":"Mesinkovska","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,25]]},"reference":[{"issue":"110","key":"e_1_2_8_2_1","first-page":"32","article-title":"A dermatologic perspective on autoinflammatory diseases","volume":"36","author":"Marzano AV","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.0878"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.02.013"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.020"},{"key":"e_1_2_8_6_1","article-title":"Prevalence of patients with self\u2010reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross\u2010sectional study","author":"Riis PT","journal-title":"Br J Dermatol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.372"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.142517"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14894"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-018-1867-z"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.01.009"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13606"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7315274"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-017-1658-0"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v11.i4.391"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.05.102"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13985"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S111019"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.6264"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14024"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15226"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210901"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.07.012"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2017.44.3.228"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2018.7859"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313481808400328"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_8_28_1","unstructured":"ChoiF.Food fat and immune dysregulation \u2013 a systematic review of dietary and metabolic factors in the pathogenesis of hidradenitis suppurativa. 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