{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:15:04Z","timestamp":1770977704453,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>COVID\u201019 cutaneous manifestations have been recently described and classified in five different clinical patterns, including acral erythema\u2010edema (pseudo\u2010chilblain), maculopapular exanthemas, vesicular eruptions, urticarial lesions, and livedo or necrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study was to examine the skin of hospitalized patients with a confirmed diagnosis of COVID\u201019 disease and describe the real prevalence of skin manifestations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study, which included hospitalized patients in Cruces University Hospital from April 14\u201330, 2020, with a laboratory\u2010confirmed diagnosis of COVID\u201019 (with polymerase chain reaction and\/or serology tests), was conducted. Entire body surface examination was performed by experienced dermatologists to search for cutaneous manifestations related to COVID\u201019 disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From a sample of 75 patients, 14 (18.7%) developed cutaneous manifestations possibly related to COVID\u201019. We found six patients with acral erythema\u2010edema (pseudo\u2010chilblain) (42.8%), four patients with maculopapular exanthemas (28.6%), two patients with urticarial lesions (14.3%), one patient with livedo reticularis\u2010like lesions (7.15%), and one patient with vesicular eruption (7.15%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study provides a more plausible relationship between the main cutaneous patterns and COVID\u201019 in hospitalized patients as all of them had a confirmatory laboratory test. Skin manifestations are frequent but mild with spontaneous resolution. These findings are nonspecific and can be similar to other viral infections and adverse drug reactions in hospitalized patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.15180","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T18:46:47Z","timestamp":1600973207000},"page":"1353-1357","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Skin manifestations in patients hospitalized with confirmed COVID\u201019 disease: a cross\u2010sectional study in a tertiary hospital"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3463-2175","authenticated-orcid":false,"given":"Irune","family":"M\u00e9ndez Maestro","sequence":"first","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8679-7756","authenticated-orcid":false,"given":"Lander","family":"Pe\u00f1a Merino","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Udondo Gonz\u00e1lez del T\u00e1nago","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aida","family":"Aramburu Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Orbea Sope\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"S\u00e1nchez De Vicente","sequence":"additional","affiliation":[{"name":"Department of Allergology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan A.","family":"Rat\u00f3n Nieto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvira","family":"Acebo Mari\u00f1as","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Gardeazabal Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cruces University Hospital Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1097"},{"key":"e_1_2_7_3_1","unstructured":"European Centre for Disease Prevention and Control.Case definition and European surveillance for COVID\u201019 as of 2 March 2020.2020.https:\/\/www.ecdc.europa.eu\/en\/case\u2010definition\u2010and\u2010european\u2010surveillance\u2010humaninfection\u2010novel\u2010coronavirus\u20102019\u2010ncov. 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