{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T21:49:54Z","timestamp":1774475394692,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Digital clubbing is a well\u2010known clinical sign characterized by thickening of the distal phalanges of the fingers and toes. Unilateral clubbing occurs less frequently. A previous report showed for the first time two cases of unilateral clubbing as a clinical manifestation of lower limb venous malformation. The objective of the present study is to describe a series of 13 patients with a low\u2010flow vascular malformation where a clubbing\u2010like unilateral digital thickening is also observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients were retrospectively included after reviewing clinical photographs from a vascular malformations database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 13 patients with low\u2010flow vascular malformations were included in this study. The mean age at diagnosis was 11\u00a0years (range 5\u201326\u00a0years) with a female predominance (nine patients). The most frequent vascular malformation collected was a blue rubber bleb nevus syndrome in four patients, followed by common venous malformations in three patients. All patients characteristically exhibited a clubbing\u2010like digital thickening. Seven patients had foot involvement and six patients hand involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although the number of cases is limited, our study is the first series of cases where a clubbing\u2010like digital thickening is described in patients with a low\u2010flow vascular malformation. The unilateral presence of clubbing or pseudoclubbing should lead to the suspicion of an underlying vascular malformation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.15585","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T07:15:53Z","timestamp":1618298153000},"page":"1248-1252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Unilateral clubbing\u2010like digital thickening as a clinical manifestation of low\u2010flow vascular malformations: a series of 13 cases"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1359-9924","authenticated-orcid":false,"given":"Fernando","family":"Garc\u00eda\u2010Souto","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Universitario de Valme Sevilla Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan 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