{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:01:35Z","timestamp":1790359295445,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T00:00:00Z","timestamp":1619395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Nigella sativa<\/jats:italic> (<jats:italic>N. sativa<\/jats:italic>) is a widely used medicinal herb with a rich cultural and religious history in Unani, Ayurveda, Chinese, and Arabic medicine. <jats:italic>N. sativa<\/jats:italic> contains many natural bioactive agents including alkaloids, saponins, alpha\u2010hederin, and thymoquinone that contribute to its broad range of benefits as a diuretic, bronchodilator, antihypertensive, antidiabetic, and analgesic. In addition, <jats:italic>N. sativa<\/jats:italic> possesses antimicrobial, anti\u2010inflammatory, and antineoplastic effects, making it an interesting potential therapy for the treatment of dermatological conditions. This article reviews the current literature surrounding the pharmacological effects of <jats:italic>N. sativa<\/jats:italic> for the treatment of acne vulgaris, melanoma, vitiligo, atopic dermatitis, plaque psoriasis, and wound healing.<\/jats:p>","DOI":"10.1111\/ijd.15615","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T09:12:24Z","timestamp":1619428344000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["A review of <i>Nigella sativa<\/i> plant\u2010based therapy in dermatology"],"prefix":"10.1111","volume":"60","author":[{"given":"Jacqueline R.","family":"Hwang","sequence":"first","affiliation":[{"name":"University of Maryland School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Cartron","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine Baltimore MD 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