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Treatment sessions were repeated at 30\u2010day intervals until patient satisfaction. The primary outcome was repigmentation of the lesions, assessed independently by two dermatologists and by the patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The MMP<jats:sup>\u00ae<\/jats:sup> technique injected 0.048\u2009mg\/cm<jats:sup>2<\/jats:sup> of 5\u2010FU or 0.0028 U\/cm<jats:sup>2<\/jats:sup> of bleomycin. The accumulated 5\u2010FU and bleomycin density per patient ranged from 0.02 to 0.77\u2009mg and 0.0022 to 0.2800 U\/ml, respectively. Patients were treated with 1 to 6 MMP<jats:sup>\u00ae<\/jats:sup> sessions with 5\u2010FU (3 patients), bleomycin (6 patients), or both drugs (2 patients). After the last session, all patients had a significant improvement (&gt;75%) of the lesions compared to baseline. There were no procedure\u2010related short\u2010 or long\u2010term adverse effects in any of the participants up to their last follow\u2010up visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The injection of antifibrotic agents using the MMP<jats:sup>\u00ae<\/jats:sup> technique was effective and safe in the treatment of hypochromic lesions. This can be a new therapeutic option for these lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.15725","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T10:57:11Z","timestamp":1624705031000},"page":"71-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Is it possible to repigment iatrogenic and traumatic hypochromic lesions? 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