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<jats:italic>Fusarium oxysporum<\/jats:italic> using the human nail, in an ex\u00a0vivo model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The kinetic of biofilm production and infection by <jats:italic>F. oxysporum<\/jats:italic> using the nail as the only nutritional source were evaluated by scanning electron microscopy, number of culturable cells, metabolic activity, characterization of extracellular matrix, spectroscopy and histopathology analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After evaluating the biofilm kinetic over 7 days using different parameters and techniques, it was possible to characterize the <jats:italic>Fusarium<\/jats:italic>\u2010nail interaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study is a part of a big project aiming to clarify the fusarial pathogenesis and contributes to proving <jats:italic>F. oxysporum<\/jats:italic> is able to adapt, grow, develop, and form a biofilm on healthy human nails, which are crucial steps for the invasion process.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.15747","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T05:08:54Z","timestamp":1625720934000},"page":"191-198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Characterization of a biofilm formed by <i>Fusarium oxysporum<\/i> on the human nails"],"prefix":"10.1111","volume":"61","author":[{"given":"Flavia Franco","family":"Veiga","sequence":"first","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas e Biomedicina Universidade Estadual de Maring\u00e1 (UEM) Maring\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidiane Vizioli","family":"de Castro\u2010Hoshino","sequence":"additional","affiliation":[{"name":"Departamento de F\u00edsica Universidade Estadual de Maring\u00e1 (UEM) Maring\u00e1 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