{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:05:17Z","timestamp":1789430717384,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T00:00:00Z","timestamp":1631404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In addition to general measures, pharmacological treatment is the basis of the management of scabies. No recent data in real\u2010life are available on the efficacy and safety of 10% benzyl benzoate emulsion for skin application administered as monotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This prospective, multicenter, French observational study comprised a registry and a prospective cohort with a follow\u2010up at 28\u2009days and a telephone call at week 12. To participate in the registry, patients had to be over 1 month old, ambulatory, presenting common, nonhyperkeratotic, untreated scabies. To be included in the cohort, patients had to be included in the registry and treated with two applications of 10% benzyl benzoate emulsion 8\u2009days apart. The primary endpoint was cure at day 28.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 186 patients included in the registry, 116 were included in the cohort. Fourteen patients were included in the cohort without being included in the registry, which led to a total of 130 patients in the cohort. At day 28, 119\/130 (91.5%; 95% CI 85.4\u201395.6%) were clinically cured. The cure was confirmed by dermoscopy in 44\/47 patients (93%). Among the 130 patients, the cure rate was 82% at week 12. Of the 119 patients cured at day 28, the rate of cure at week 12 was 89.9%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In real life, two applications of 10% benzyl benzoate emulsion 8\u2009days apart provides high cure rates in patients with common scabies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.15879","type":"journal-article","created":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T19:01:00Z","timestamp":1631473260000},"page":"434-441","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A prospective cohort of patients with common scabies treated with 10% benzyl benzoate emulsion as monotherapy: EPIGALE study"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0685-7262","authenticated-orcid":false,"given":"Eric","family":"Caumes","sequence":"first","affiliation":[{"name":"Service de Maladies infectieuses et Tropicales Sorbonne Universit\u00e9 INSERM 1136 Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique Assistance Publique\u2010H\u00f4pitaux de Paris H\u00f4pitaux Universitaires Piti\u00e9\u2010Salp\u00eatri\u00e8re Charles Foix Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2973-5257","authenticated-orcid":false,"given":"Marc","family":"Marty","sequence":"additional","affiliation":[{"name":"Clinical Research Department Nukleus Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Cadot","sequence":"additional","affiliation":[{"name":"Dermatology Office La Varenne Saint Hilaire France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Boulanger","sequence":"additional","affiliation":[{"name":"Zambon France Issy\u2010les\u2010Moulineaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Rousseaux","sequence":"additional","affiliation":[{"name":"Clinical Research Department Nukleus Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Petit","sequence":"additional","affiliation":[{"name":"Dermatology Department Assistance Publique\u2010H\u00f4pitaux de Paris H\u00f4pital Saint Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68772-2"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp052784"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14351"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13152"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.07.025"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000495290"},{"key":"e_1_2_7_8_1","article-title":"Interventions for treating scabies","volume":"2007","author":"Strong M","year":"2007","journal-title":"Cochrane Database System Rev"},{"key":"e_1_2_7_9_1","first-page":"757","article-title":"The treatment of scabies. 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