{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:17:57Z","timestamp":1758273477766,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:00:00Z","timestamp":1643500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hydrogen peroxide (H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>) has been used in medicine as an antiseptic, but at a higher concentration of 40%, it is used as a chemical cauterant for seborrheic keratoses (SKs). Its action and hence utility at 30% is unexplored. It can serve as a relatively inexpensive modality of treatment for SKs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the efficacy and side effects of 30% H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> as a chemical cauterant in SKs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seborrheic keratoses were treated with 30% H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> methodically. Posttreatment assessment was done for the lesion thickness, patient satisfaction, and side effects like burning, itching, edema, crusting, vesiculation, erosion, ulceration, and pigmentary changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete clearance was noted in 25 (49%) lesions, after a single session. Five (9%) lesions responded poorly. Patient satisfaction was excellent with 34 (66.7%) lesions. Side effects noted were burning, pruritus, erythema, edema, and crusting. However, none of them was severe. Dryness, vesiculation, and scarring were reported by none.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> 30% can be used as a chemical cauterant with minimal side effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.16096","type":"journal-article","created":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T12:53:37Z","timestamp":1643547217000},"page":"1113-1116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Utility of 30% hydrogen peroxide in the treatment of seborrheic keratosis"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1095-4310","authenticated-orcid":false,"given":"Punya","family":"Suvarna","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Kasturba Medical College, Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3314-4361","authenticated-orcid":false,"given":"Manasa Narayan","family":"Kayarkatte","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Kasturba Medical College, Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,30]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"16","article-title":"A closer look at seborrheic keratoses: patient perspectives, clinical relevance, medical necessity, and implications for management","volume":"10","author":"Del Rosso JQ","year":"2017","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.16100"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.12.1556"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.044"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-020-00433-6"},{"key":"e_1_2_8_7_1","first-page":"426","article-title":"Protective effects of Scutellaria baicalensis Georgi against hydrogen peroxide\u2010induced DNA damage and apoptosis in HaCaT human skin keratinocytes","volume":"31","author":"Yoon JJ","year":"2017","journal-title":"EXCLI J"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5107"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2014.892937"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-237008"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.2020.4974"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.16096","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.16096","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.16096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T08:10:55Z","timestamp":1713168655000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.16096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,30]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/ijd.16096"],"URL":"https:\/\/doi.org\/10.1111\/ijd.16096","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"type":"print","value":"0011-9059"},{"type":"electronic","value":"1365-4632"}],"subject":[],"published":{"date-parts":[[2022,1,30]]},"assertion":[{"value":"2021-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}