{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:25:56Z","timestamp":1792808756525,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Ocular rosacea is a special manifestation of rosacea with unknown etiology. Eye involvement in rosacea patients is surprisingly common; however, it is often underdiagnosed, resulting in inappropriate treatment. We aimed to provide an updated epidemiologic perspective on ocular rosacea in Germany to improve patient care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>Data of 777 rosacea patients were assessed using a detailed online questionnaire regarding ocular and skin symptoms, previous dermatological and ophthalmological consults, presence of type 1 hypersensitivities, and Demodex testing. All data were statistically analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Most patients reported ocular symptoms (399\/777, 51.4%), including red eyes (179\/399, 44.9%), itching (187\/399, 46.9%), sty or chalazion (309\/399, 77.4%), and dryness (108\/399, 27.1%). Ocular rosacea was confirmed in 149\/309 cases who consulted an ophthalmologist (45.3%). A total of 159\/399 (39.8%) had no pre\u2010existing allergies. Eye involvement was significantly associated with the presence of skin symptoms (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05), impacting patients' general well\u2010being and overall treatment satisfaction. About half of Demodex\u2010positive patients (21\/45, 46.7%) showed ocular symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Eye involvement in rosacea patients was common, often presenting with unspecific symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.16235","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T08:24:41Z","timestamp":1652775881000},"page":"880-885","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical clues to identify patients with ocular rosacea \u2013 a Germany\u2010wide epidemiologic analysis"],"prefix":"10.1111","volume":"61","author":[{"given":"Stephan","family":"Zierl","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital of Munich (LMU)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5451-8038","authenticated-orcid":false,"given":"Johannes A.","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital of Munich (LMU)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6865-0526","authenticated-orcid":false,"given":"Anne","family":"Guertler","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital of Munich (LMU)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3174-163X","authenticated-orcid":false,"given":"Cecilia","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital of Munich (LMU)  Munich 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