{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:52:17Z","timestamp":1787014337107,"version":"build-2736575974"},"reference-count":70,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Studies focusing on the relationship between periodontitis and systemic diseases have suggested a possible association between these two chronic and inflammatory disorders. We aimed to comparatively investigate the salivary oxidative status, biomarker levels, clinical findings, and the microbial load on subgingival biofilm samples in psoriasis patients and controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty participants were allocated into four groups as follows: (1) systemically and periodontally healthy (C group); (2) systemically healthy with periodontitis (P group); (3) psoriasis (Ps) and periodontally healthy (Ps\u2010C group); and (4) Ps with periodontitis (Ps\u2010P group). Subgingival biofilm samples were obtained to detect the periodontopathogenic agents by Real\u2010time PCR (qPCR). The total antioxidant status (TAS) (mmol\/l), total oxidant status (TOS) (\u03bcmol\/l), and arylesterase (ARE) activity (U\/L) were analyzed using saliva samples.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The level of TOS and oxidative stress index (OSI) were significantly higher in patients with Ps\u2010P and P compared to controls (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001, and\n                      <jats:italic>P<\/jats:italic>\n                      \u2009\u02c2\u20090.001, respectively). ARE levels were higher in controls compared to Ps and P (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009\u02c2\u20090.001). The prevalences of bacteria detected in subgingival biofilm samples were similar between all groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study reported that psoriasis may amplify TOS and OSI, and the co\u2010existence of psoriasis and periodontitis may aggravate oxidative stress.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.16353","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T16:49:47Z","timestamp":1659199787000},"page":"1487-1496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The link between total antioxidant status, total oxidant status, arylesterase activity, and subgingival microbiota in psoriasis patients"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6204-7304","authenticated-orcid":false,"given":"Tu\u011f\u00e7e","family":"Paksoy","sequence":"first","affiliation":[{"name":"Istanbul Atlas University, Faculty of Dentistry Department of Periodontology  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclbahar","family":"Ustao\u011flu","sequence":"additional","affiliation":[{"name":"Bolu Abant Izzet Baysal University, Faculty of Dentistry Department of Periodontology  Bolu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Yaman","sequence":"additional","affiliation":[{"name":"Bolu Abant Izzet Baysal University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery  Bolu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zkan","family":"Ar\u0131\u00f6z","sequence":"additional","affiliation":[{"name":"Bolu Abant Izzet Baysal 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