{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T21:19:52Z","timestamp":1781731192965,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is sparse data regarding total body nevus count (TBNC), nevus count in specific locations, phenotypic factors, anthropometric indices, sunburn, and the relation to multiple primary cutaneous melanomas (MPCM) development. We aim to compare these variables in a cohort of patients diagnosed with single primary melanoma (SPM) and MPCM with histologic diagnoses of melanoma in\u2009situ, superficial spreading, and nodular melanoma in our clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective observational studies for the evaluation of nevus counts in biopsy\u2010proven melanoma patients from 2017 to 2020 at Ankara University were conducted. Age, gender, family history of melanoma, increased sun exposure, nonmelanoma skin cancers (NMSC), height, sunburn history, TBNC, and nevi count in specific anatomical locations were evaluated by multivariate logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total number of 156 patients consisting of 22 MPCM and 134 SPM were included. Mean TBNC for SPM vs MPCM patients were 96.87 (<jats:italic>SD<\/jats:italic>\u2009\u00b1\u2009124.71) vs 247.00 (<jats:italic>SD<\/jats:italic>\u2009\u00b1\u2009261.58), respectively (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). TBNC was correlated to the left arm, trunk, lower extremity, and head and neck nevus counts but not with the right arm nevus count. Multiple regression analysis showed that having more than 10 nevi on the head and neck area is associated with MPCM (OR, 3.882 [95% CI, 1.084\u201313.899]). TBNC and nevus count in specific locations were found to be significantly higher in MPCM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk of MPCM was associated with having \u226510 nevi on the head and neck.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.16432","type":"journal-article","created":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T08:27:06Z","timestamp":1666081626000},"page":"66-72","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of phenotypic features in patients with single vs multiple primary cutaneous melanomas: a prospective single\u2010center study"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4748-1556","authenticated-orcid":false,"given":"Banu","family":"Farabi","sequence":"first","affiliation":[{"name":"Dermatology Department, New York Medical College Metropolitan Hospital Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seher","family":"Bostanci","sequence":"additional","affiliation":[{"name":"Dermatology Department Ankara University School of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bengu Nisa","family":"Akay","sequence":"additional","affiliation":[{"name":"Dermatology Department Ankara University School of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Caliskan","sequence":"additional","affiliation":[{"name":"Public Health Department Ankara University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Fatih","family":"Atak","sequence":"additional","affiliation":[{"name":"Dermatology Department Ankara University School of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000053"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.10.015"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2016.05.005"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.115"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21001"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.149"},{"key":"e_1_2_8_8_1","unstructured":"SEER.Cancer stat facts: Melanoma of the skin.National Cancer Institute;2021[cited 2021. 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