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As of today, its physiopathology remains incompletely understood, and there are no standardized guidelines regarding its management. Here, we conduct a literature review of the reported cases of drug\u2010induced accelerated nodulosis and add our case of a 79\u2010year\u2010old female with an atypical clinical presentation.<\/jats:p>","DOI":"10.1111\/ijd.16549","type":"journal-article","created":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T20:40:47Z","timestamp":1670964047000},"page":"432-440","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Drug\u2010induced accelerated nodulosis: review of the literature"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6805-1790","authenticated-orcid":false,"given":"Ana G.","family":"Palmeiro","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Egas Moniz  Rua da Junqueira 126 1349\u2010019 Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria H.","family":"Louren\u00e7o","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Hospital Egas Moniz  Lisbon Portugal"},{"name":"CEDOC (Chronic Diseases Research Center) NOVA Medical School  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Miroux\u2010Catarino","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Egas Moniz  Rua da Junqueira 126 1349\u2010019 Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas","family":"Crispim","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Hospital Egas Moniz  Lisbon Portugal"},{"name":"NOVA Medical School, NOVA Lisbon University  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime C.","family":"Branco","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Hospital Egas Moniz  Lisbon Portugal"},{"name":"CEDOC (Chronic Diseases Research Center) NOVA Medical School  Lisbon Portugal"},{"name":"NOVA Medical School, NOVA Lisbon University  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Viana","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Egas Moniz  Rua da Junqueira 126 1349\u2010019 Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab613"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.03.004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1720"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201502-0364IM"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20153750"},{"key":"e_1_2_7_7_1","first-page":"867","article-title":"Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. 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