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In the U.S., the current syphilis epidemic is disproportionately impacting communities that have been historically underserved in medicine. These include men who have sex with men, especially those infected with HIV; people of color; and reproductive\u2010age women with poor access to prenatal care. With syphilis now being more commonly diagnosed in non\u2010STI than STI clinics in all genders, and since primary and secondary syphilis and congenital syphilis present with characteristic mucocutaneous manifestations, dermatologists are in a position to help reduce the advance of this preventable epidemic, by actively considering this diagnosis and incorporating syphilis screening into their practice. Herein, we delineate strategies by which dermatologists can contribute to this critical effort in their roles as clinicians, public health advocates, and researchers. In particular, we discuss the rapidly changing demographics of syphilis, nuances in serologic testing and treatment, strategies to increase public healthcare access and equity in these underserved populations, and research gaps in this field.<\/jats:p>","DOI":"10.1111\/ijd.16574","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T02:34:13Z","timestamp":1672799653000},"page":"583-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Syphilis: recommendations for dermatologists on a resurgent epidemic"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4705-181X","authenticated-orcid":false,"given":"Antonio","family":"Ji\u2010Xu","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California  Davis, Sacramento CA USA"},{"name":"Department of Dermatology University of California, San Francisco School of Medicine, Zuckerberg San Francisco General Hospital  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kieron S.","family":"Leslie","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California  Davis, Sacramento CA USA"},{"name":"Department of Dermatology University of California, San Francisco School of Medicine, Zuckerberg San Francisco General Hospital  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,3]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Centers for Disease Control and Prevention.Syphilis elimination effort (SEE).https:\/\/www.cdc.gov\/stopsyphilis\/media\/SyphRate11-28-01.htm. 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