{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:52:22Z","timestamp":1787014342393,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T00:00:00Z","timestamp":1684540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Incidence of cutaneous melanoma is steadily growing, and its early recognition is of paramount importance. Small, pigmented lesions often represent a challenge for the clinician, as predictors of melanoma have not yet been uniquely identified in this setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify dermoscopic features that aid in distinguishing small diameter melanomas (\u22645\u2009mm) from equivocal melanocytic nevi measuring \u22645\u2009mm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective multicenter study was conducted to collect demographics, clinical and dermoscopic pictures of (i) histology\u2010proven flat melanomas, measuring \u22645\u2009mm, (ii) histology\u2010proven but clinically\/dermoscopically equivocal melanocytic nevi measuring \u22645\u2009mm, and (iii) histology\u2010proven flat melanomas, measuring &gt;5\u2009mm. An independent dermoscopic evaluation was performed. Differences in predefined dermoscopic features were assessed across the three groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 103 melanomas measuring \u22645\u2009mm were collected; 166 control lesions, comprising 85 large (&gt;5\u2009mm) melanomas and 81 dubious, clinically equivocal melanocytic nevi measuring \u22645\u2009mm were included. Of the 103 mini\u2010melanomas, only 44 were melanoma\n                      <jats:italic>in situ<\/jats:italic>\n                      . Five dermoscopic predictors of melanoma were identified for the assessment of flat, non\u2010facial melanocytic lesions measuring \u22645\u2009mm, namely: atypical pigment network, blue\u2010white veil, pseudopods, peripheral radial streaks, and presence of more than one color. The latter were combined into a predictive model capable of identifying melanoma with 65% sensitivity and 86.4% specificity, at a cut\u2010off score of 3. Among melanomas measuring \u22645\u2009mm, presence of a blue\u2010white veil (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0027) or negative pigment network (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0063) was associated with invasiveness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A set of five dermoscopic predictors of melanoma, atypical pigment network, blue\u2010white veil, pseudopods, peripheral radial streaks, and presence of more than one color is proposed for the assessment of flat, non\u2010facial melanocytic lesions measuring \u22645\u2009mm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.16710","type":"journal-article","created":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T04:30:17Z","timestamp":1684557017000},"page":"1040-1049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Dermoscopic predictors of melanoma in small diameter melanocytic lesions (mini\u2010melanoma): a retrospective multicentric study of 269 cases"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8534-6497","authenticated-orcid":false,"given":"Gianluca","family":"Nazzaro","sequence":"first","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9449-849X","authenticated-orcid":false,"given":"Carlo A.","family":"Maronese","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3718-1784","authenticated-orcid":false,"given":"Giovanni","family":"Casazza","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Community Health \u2013 Laboratory of Medical Statistics, Biometry and Epidemiology \u201cG.A. Maccacaro\u201d Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0464-3356","authenticated-orcid":false,"given":"Serena","family":"Giacalone","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5664-2657","authenticated-orcid":false,"given":"Cristina B.","family":"Spigariolo","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"},{"name":"Department of Pathophysiology and Transplantation Universit\u00e0 degli Studi di Milano  Milan 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