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Latin American populations have unique attributes that must be considered as part of this process to improve clinical success and achieve patient goals. Acne is more common among patients with darker skin phototypes, in whom it is often associated with postinflammatory hyperpigmentation and scarring\u2014the most important acne sequelae\u2014potentially due to more frequent and more severe underlying inflammatory processes in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These data argue for an early and proactive approach to managing acne in these patients with agents that target the inflammatory processes that underlie acne and its sequelae. As a class, retinoids offer a spectrum of activity that may be useful in addressing the unique needs of Latin American populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Trifarotene, a novel, selective retinoid, has been evaluated in relevant patient populations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.16754","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T08:01:34Z","timestamp":1687334494000},"page":"1176-1185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Acne characteristics in Latin American patients and the potential role of trifarotene"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1090-177X","authenticated-orcid":false,"given":"Marco A. 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