{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T01:16:36Z","timestamp":1773018996783,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Microneedling is a technique of repeated puncturing or drilling of the skin to induce repair and collagen induction. There are many reported important factors determining the efficacy of microneedling treatment. The extent of injury needed to produce the desired effect in each condition is one of these important factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We designed the present split\u2010face comparative study to evaluate the use and effectiveness of two different depths of penetration of Dermapen needles in the management of atrophic postacne scars.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>The present study involved 14 subjects with atrophic postacne scars. In each patient, both sides of the face were treated with six sessions of microneedling, using Dermapen at 2\u2010week intervals. A split\u2010face study design was performed. The right (Rt) side of the face was treated with Dermapen using 2.5\u2009mm needle length, while the left (Lt) side was treated using 1.5\u2009mm needle length.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a significantly better percentage of improvement of acne scars on the Rt side of the face compared to the Lt side (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.02) after six sessions. Both sides of the face showed improvement of collagen bundles and elastic fibers characteristics after six sessions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of 2.5\u2009mm depth proved to be more effective both clinically and histologically in the management of atrophic postacne scars.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.17006","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T10:34:20Z","timestamp":1703932460000},"page":"632-638","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of microneedling depth of penetration in management of atrophic acne scars: a split\u2010face comparative study"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8921-2442","authenticated-orcid":false,"given":"Moetaz","family":"El\u2010Domyati","sequence":"first","affiliation":[{"name":"Department of Dermatology, STD's and Andrology, Faculty of Medicine Minia University  Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noha H.","family":"Moftah","sequence":"additional","affiliation":[{"name":"Department of Dermatology, STD's and Andrology, Faculty of Medicine Minia University  Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmaa M.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Dermatology, STD's and Andrology, Faculty of Medicine Minia University  Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel R.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, STD's and Andrology, Faculty of Medicine Minia University  Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S142450"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12761"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200001010-00001"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.113451"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2012.742949"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2011.00583.x"},{"issue":"7","key":"e_1_2_5_8_1","first-page":"36","article-title":"Microneedling therapy for atrophic acne scars: an objective evaluation","volume":"8","author":"El\u2010Domyati M","year":"2015","journal-title":"J Clin Aesthet 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