{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:12:30Z","timestamp":1791389550833,"version":"4.3.3"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are a limited number of studies evaluating the effects of alopecia areata (AA) on the health\u2010related quality of life (HRQoL) of pediatric patients and their families. This study aimed to assess the HRQoL of pediatric patients with AA and their parents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This single\u2010center cross\u2010sectional cohort study included 72 pediatric patients diagnosed with AA. The study was conducted between December 2020 and December 2021 in the dermatology department of a single tertiary center in Turkey. The HRQoL index of the pediatric patients was assessed with the Children's Dermatology Life Quality Index (CDLQI). At the same time, their parents, who were primarily involved in the disease process, were evaluated using the Dermatological Family Impact Scale (DeFIS). An ordinal logistic regression model was used to detect predictors for CDLQI severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean\u2009\u00b1\u2009SD CDLQI of the pediatric patients who participated in our study was 8.4\u2009\u00b1\u20095.3, corresponding to moderate impairment. The highest impairment in CDLQI was observed in the symptoms and feelings domain, while the slightest impairment was observed in the domain of personal relationships (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). There was a statistically significant positive correlation between the Severity of Alopecia Tool (SALT) score and all CDLQI domains, and the most substantial relationship was with the leisure domain (<jats:italic>r<\/jats:italic>\u2009=\u20090.78, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). DeFIS scores of female patients were substantially higher than males (25.3\u2009\u00b1\u20098.6 vs. 17.6\u2009\u00b1\u20099, <jats:italic>P<\/jats:italic>\u2009=\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study supports that AA is a disease that significantly impacts the HRQoL of affected children and their families.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.17154","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T11:38:33Z","timestamp":1713785913000},"page":"1414-1420","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of quality of life scores and family impact scales in pediatric patients with alopecia areata: a cross\u2010sectional cohort study"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9170-4262","authenticated-orcid":false,"given":"Sera Nur","family":"Y\u00fccesoy","sequence":"first","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Dermatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba Kevser","family":"Uzun\u00e7akmak","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Dermatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zge","family":"Sel\u00e7uko\u011flu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Ministry of Health, Arnavutk\u00f6y State Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zge","family":"A\u015fk\u0131n","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Dermatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tumay","family":"Ak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fenur","family":"\u00d6zdil Eser","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Ministry of Health, Sultan 2. Abdulhamid Han Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eenol","family":"Turan","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Psychiatry Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Server","family":"Serdaro\u011flu","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Dermatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2018.12.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14497"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.135525"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S424374"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16953.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4274\/turkderm.27167"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1054898"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2017.07.001"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18926"},{"issue":"1","key":"e_1_2_8_11_1","first-page":"121","article-title":"Severity stratification of Children's Dermatology Life Quality Index (CDLQI) scores","volume":"163","author":"Waters A","year":"2010","journal-title":"Br J Dermatol"},{"key":"e_1_2_8_12_1","first-page":"71402a","article-title":"Cross validation of the Turkish version of Children's Dermatology Life Quality Index","volume":"1","author":"Didar Balc\u0131 D","year":"2007","journal-title":"J Turk Acad Dermatol"},{"issue":"3","key":"e_1_2_8_13_1","first-page":"69","article-title":"Statistics corner: a guide to appropriate use of correlation coefficient in medical research","volume":"24","author":"Mukaka MM","year":"2012","journal-title":"Malawi Med J"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.12.051"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.01.048"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000466704"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12315"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000497166"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.21.202"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14676"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T05:46:18Z","timestamp":1744004778000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.17154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,22]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/ijd.17154"],"URL":"https:\/\/doi.org\/10.1111\/ijd.17154","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,22]]},"assertion":[{"value":"2024-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}