{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T01:17:47Z","timestamp":1773019067644,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The clinical appearance of cutaneous leishmaniasis (CL) lesions located in the nasal area can be confused with many inflammatory or tumoral diseases. In this study, we aimed to determine the frequency of nasal involvement and the morphological variants of CL lesions located in the nasal region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective study, we included patients who presented to our Skin and Venereal Diseases Clinic in the province of \u015eanl\u0131urfa, located in the Southeastern Anatolia region of Turkey between September 2022 and October 2023, and were diagnosed with CL with nasal involvement. From the records of CL patients with nasal involvement in our clinic, we evaluated the clinical (lesion location, lesion type, lesion diameter, lesion duration, treatment) and demographic characteristics (age, gender).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009278) diagnosed with CL using microscopic examination, 34 had nasal involvement, and the nasal involvement rate was 12.2%. Nineteen (55.8%) of the patients with nasal involvement were male, and 15 (44.2%) were female. Acute CL was detected in 28 patients (16 patients with dry\u2010type lesions, 12 patients with wet\u2010type lesions), and chronic CL was detected in six patients (four patients with lupoid and two patients with recidivant type lesions). According to the frequency distribution of clinical appearance, the most common lesions were eczema\u2010like lesions, erysipeloid\u2010type lesions, rhinophyma\u2010like lesions, and lymphoma\u2010like lesions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Physicians working in CL\u2010endemic regions should strictly consider CL in the differential diagnosis of nasal lesions. Early diagnosis and treatment of CL might prevent possible scarring and mucosal spread.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.17284","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:22:57Z","timestamp":1717719777000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical spectrum of nasal involvement in cutaneous leishmaniasis"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3366-4551","authenticated-orcid":false,"given":"\u0130sa","family":"An","sequence":"first","affiliation":[{"name":"Department of Dermatology, \u015eanl\u0131urfa Training and Research Hospital  \u015eanl\u0131urfa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nebiye Yentur","family":"Doni","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Harran University Medical Faculty  \u015eanl\u0131urfa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2019.01.002"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035671"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.13730"},{"issue":"2","key":"e_1_2_7_5_1","first-page":"125","article-title":"Cutaneous leishmaniasis","volume":"10","author":"Harman M","year":"2017","journal-title":"Turkiye Klinikleri J Dermatol\u2010Special Topics"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14002"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2019.10.008"},{"issue":"3","key":"e_1_2_7_8_1","first-page":"202","article-title":"Nasal involvement of cutaneous leishmaniasis","volume":"24","author":"Khan MI","year":"2010","journal-title":"JPMI"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2005.72.819"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.14127"},{"issue":"3","key":"e_1_2_7_11_1","first-page":"146","article-title":"Clinical spectrum of nasal leishmaniasis in Muzaffarabad","volume":"19","author":"Bari AU","year":"2009","journal-title":"J Coll Physicians Surg Pak"},{"issue":"3","key":"e_1_2_7_12_1","first-page":"376","article-title":"Dermatologic and otorhinolaryngologic manifestations in Leishmaniasis","volume":"15","author":"Mota LAA","year":"2011","journal-title":"Intl Arch Otorhinolaryngol"},{"issue":"1","key":"e_1_2_7_13_1","first-page":"3","article-title":"Ear, nose and throat manifestations of mucocutaneous Leishmaniasis: a literature review","volume":"85","author":"Marra F","year":"2014","journal-title":"Acta Biomed"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.2007.00944.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12507"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2010.09.008"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.18-0578"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.5455\/annalsmedres.2019.11.708"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_420_16"},{"issue":"3","key":"e_1_2_7_20_1","first-page":"10","article-title":"Rhinophymous leishmaniasis: a new variant","volume":"15","author":"Ul Bari A","year":"2009","journal-title":"Dermatol Online J"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2013.02.024"},{"issue":"4","key":"e_1_2_7_22_1","first-page":"455","article-title":"Studies on the attraction of Simulium damnosum sl (Diptera: Simuliidae) to its hosts. I. The relative importance of sight, exhaled breath, and smell","volume":"27","author":"Thompson BH","year":"1976","journal-title":"Tropenmed Parasitol"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2014.06.007"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.58698"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2017.05.022"},{"key":"e_1_2_7_26_1","first-page":"1","article-title":"Localization of Lupoid Leishmaniasis on the face: a case control study","volume":"3","author":"Yazdanpanah MJ","year":"2024","journal-title":"JEADV Clin Pract"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.16278"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.16-0349"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/805108"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.4274\/tdd.galenos.2018.3812"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/15569527.2019.1610887"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15706"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.17284","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:22:54Z","timestamp":1773015774000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.17284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,6]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/ijd.17284"],"URL":"https:\/\/doi.org\/10.1111\/ijd.17284","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,6]]},"assertion":[{"value":"2024-01-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}