{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T04:06:28Z","timestamp":1744085188049,"version":"3.40.3"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T00:00:00Z","timestamp":1717632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Device\u2010related infective endocarditis (IE) is associated with high mortality, resulting in a growing emphasis on identifying and managing comorbidities that increase the risk of IE in these patients. Psoriasis is increasingly being recognized as having multiple cardiovascular manifestations. However, little is known about the impact of psoriasis on IE risk in patients with permanent pacemakers (PPM). Our study aimed to assess whether psoriasis is associated with an increased risk of developing IE in patients with PPM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The National Inpatient Sample database was utilized to extract patients with PPM. The presence of psoriasis stratified patients. Demographic and comorbidity data were collected. 1:10,000 propensity matching for IE risk factors was performed to examine independent associations between psoriasis and IE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 437,793 patients, 45 had psoriasis. Psoriasis patients had higher IE rates (4.4% vs. 0.6%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). On multivariate analysis, psoriasis was associated with a 7.2\u2010fold high IE risk (OR: 7.2 [1.7\u201330.2]; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Post\u2010match analysis showed an 8.3\u2010fold IE risk in psoriasis patients (OR: 8.3 [2.0\u201334.4]; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Psoriasis was independently associated with elevated IE risk in patients with PPM. Further studies are required to corroborate these findings, which will have implications for IE prophylaxis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.17292","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T04:28:57Z","timestamp":1717734537000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of psoriasis on the risk of device\u2010related infective endocarditis in patients with permanent pacemakers: a propensity\u2010matched analysis"],"prefix":"10.1111","volume":"63","author":[{"given":"Chapman","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Medicine Northwell Health  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nawal","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwell Health  New York NY 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