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Its global impact is considerable, affecting more than 200\u2009million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin\u2010to\u2010skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations. This review presents consensus\u2010based clinical practice guidelines for diagnosing and managing scabies, developed through the fuzzy Delphi method by dermatology, parasitology, pediatrics, pharmacology, and public health experts. The presence of burrows containing adult female mites, their eggs, and excreta is the diagnostic hallmark of scabies. Definitive diagnosis typically involves direct microscopic examination of skin scrapings obtained from these burrows, although dermoscopy has become a diagnostic tool in clinical practice. Treatment modalities encompass topical agents, such as permethrin, balsam of Peru, precipitated sulfur, and benzyl benzoate. In cases where topical therapy proves inadequate or in instances of crusted scabies, oral ivermectin is recommended as a systemic treatment option. This comprehensive approach addresses the diagnostic and therapeutic challenges associated with scabies, optimizing patient care, and management outcomes.\n                  <\/jats:p>","DOI":"10.1111\/ijd.17327","type":"journal-article","created":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T23:18:36Z","timestamp":1719184716000},"page":"1642-1656","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Clinical practice guidelines for the diagnosis and treatment of scabies"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7059-5474","authenticated-orcid":false,"given":"Soner","family":"Uzun","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Akdeniz University Faculty of Medicine  Antalya 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