{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T22:50:36Z","timestamp":1782773436894,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Skin cancer is a primary health concern in renal transplant recipients (RTRs). Existing research mainly stems from North America, Europe, and Australia, with limited data from Latin America.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This 56\u2010year (1967\u20132023) retrospective cohort study explores skin cancer incidence in Mexican RTRs. Our objective was to assess the long\u2010term incidence of malignant cutaneous neoplasms in Mexican RTRs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over 56\u2009years, 1642 RTRs (58% male) were studied. Median follow\u2010up was 8.4\u2009years; median age at transplantation was 32.6\u2009years. Skin cancer incidence was 6.6% (95% CI: 5.5\u20137.9), with an incidence density rate of 6.5 (95% CI: 5.4\u20137.9) per 1000 person\u2010years and a median latency of 9.8\u2009years. Incidence increased with longer transplantation\u2010related immunosuppression (TRI), with a relative risk for &gt;30\u2009years of TRI of 4.8 (95% CI: 2.6\u20139.1) for any skin cancer and 7.5 (95% CI: 3.8\u201314.6) for squamous cell carcinoma (SCC). SCC was the most common malignancy (76.1%), followed by basal cell carcinomas (BCC), with a 3.6:1 ratio. Metastatic SCC occurred in 6.5% of skin cancer patients, with a skin cancer\u2010related mortality rate of 2.7%. Limitations of the study include its single\u2010center and retrospective design and unassessed factors such as human papillomavirus infection and sun exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study provides unique insights into the epidemiology of skin cancer among Mexican RTRs. It constitutes the largest cohort of skin cancer cases among RTRs in Mexico and, to our knowledge, in Latin America. Despite the lack of recognition of a high skin cancer incidence in non\u2010White RTRs, our 6.6% incidence underscores the need to enhance surveillance programs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.17332","type":"journal-article","created":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T03:33:29Z","timestamp":1719027209000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Skin cancer incidence in Mexican renal transplant recipients: a cohort over 56\u2009years"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7617-3915","authenticated-orcid":false,"given":"Andrea","family":"Malag\u00f3n\u2010Liceaga","sequence":"first","affiliation":[{"name":"Dermatology Department National Institute of Nutrition Salvador Zubir\u00e1n  Mexico City 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