{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T01:17:30Z","timestamp":1773019050766,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Frontal fibrosing alopecia (FFA) is a primary cicatricial alopecia characterized by hairline recession, pruritus, and facial papules (FP). Various therapies are used to stabilize disease activity and induce remission. However, FP of FFA is resistant to treatment in many cases. In this review, we searched the PubMed and Google Scholar databases to screen the published literature on treatment options for FP in the context of FFA. Overall, 12 studies were included in this review. Available literature suggests a noticeable improvement in resistant\u2010to\u2010treatment FP in FFA patients with oral isotretinoin. The available evidence is limited and is derived from retrospective studies and case reports\/series. Systemic isotretinoin can be considered a promising therapeutic regimen for treating resistant\u2010to\u2010treatment FP of FFA patients. However, more extensive, well\u2010designed studies are necessary for confirmatory evidence.<\/jats:p>","DOI":"10.1111\/ijd.17356","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T22:57:54Z","timestamp":1720738674000},"page":"1685-1690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isotretinoin as a promising option in the treatment of facial papules of frontal fibrosing alopecia"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7993-6220","authenticated-orcid":false,"given":"Amir Mohammad","family":"Beyzaee","sequence":"first","affiliation":[{"name":"Department of Dermatology Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahsa","family":"Babaei","sequence":"additional","affiliation":[{"name":"Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahare","family":"Ghoreishi","sequence":"additional","affiliation":[{"name":"Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4984-3589","authenticated-orcid":false,"given":"Anna","family":"Wa\u015bkiel\u2010Burnat","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Warsaw  Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Rudnicka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Warsaw  Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Starace","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Tosti","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Cutaneous Surgery University of Miami Miller School of Medicine  Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anant","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Dr.\u00a0DY Patil Medical College  Navi Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6751-1428","authenticated-orcid":false,"given":"Rodney","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Melbourne  Melbourne Vic. 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