{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:27:57Z","timestamp":1789687677440,"version":"4.0.1"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012331","name":"LEO Fondet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008349","name":"Boehringer Ingelheim International GmbH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008897","name":"Janssen Pharmaceutica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psoriasis significantly burdens patients' lives, but there is limited data on this in Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between May 2022 and January 2023, we conducted a cross\u2010sectional online survey of 563 Brazilian residents aged \u226518\u2009years who had been diagnosed with psoriasis. Spearman's correlation (<jats:italic>r<\/jats:italic>) was used to test the correlation between self\u2010assessed disease severity (Simplified Psoriasis Index [saSPI] extent score; range 0 [clear\/minor] to 40 [widespread\/severe]) and health\u2010related quality of life (QoL, score of 1 means perfect health) and capability (ICECAP\u2010A: score of 1 means full capability) measures. Multivariable linear regression was used to identify predictors of QoL and capability. A thematic analysis examined the free\u2010text responses and identified common themes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of participants was 42.1\u2009\u00b1\u200912.4\u2009years, and over half had at least one other long\u2010term condition. The mean QoL score was 0.59\u2009\u00b1\u20090.25, and the mean capability score was 0.71\u2009\u00b1\u20090.21. At the time of survey completion, over 80% of respondents reported some level of pain and\/or discomfort, and 86% reported feeling anxious and\/or depressed. The mean self\u2010assessed saSPI was 7.8\u2009\u00b1\u20098.6, which negatively correlated with health\u2010related QoL (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.49, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) and capability (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.44, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Significant predictors of poorer QoL and reduced capability included high saSPI, number of psoriasis flares and comorbidities, female gender, Black ethnicity, and employment status (unemployed, long\u2010term sick). Frequently reported areas that impacted patients were social stigma\/prejudice, powerlessness, lack of education and public awareness, and difficulty obtaining appropriate care\/treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found that the clinical manifestations, severity, and associated comorbidities of psoriasis negatively impacted health\u2010related QoL and capability, along with feelings of stigmatization and barriers to specialist treatment. This highlights the need for better access to care and awareness of the disease to improve the lives of people living with psoriasis in Brazil.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.17387","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T05:14:00Z","timestamp":1721279640000},"page":"325-332","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Experience of living with psoriasis in Brazil: a Global Psoriasis Atlas online survey"],"prefix":"10.1111","volume":"64","author":[{"given":"Jaquelini Barboza da","family":"Silva","sequence":"first","affiliation":[{"name":"Department of Life Sciences University of Santa Cruz do Sul  Santa Cruz do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8418-8332","authenticated-orcid":false,"given":"Alison K.","family":"Wright","sequence":"additional","affiliation":[{"name":"Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry School of Health Sciences, Faculty of Biology, Medicine and Health, NIHR Manchester Biomedical Research Centre, University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 V. E.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Psoriasis Outpatient Clinic, Hospital Moinhos de Vento  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E. M.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Centre for Dermatology Research, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre University of Manchester  Manchester UK"},{"name":"Department of Dermatology King's College Hospital, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren M.","family":"Ashcroft","sequence":"additional","affiliation":[{"name":"Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry School of Health Sciences, Faculty of Biology, Medicine and Health, NIHR Manchester Biomedical Research Centre, University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)32549\u20106"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20104\u201035"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.15721"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2017.1345749"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1590"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13604"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/PTT.S51725"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21051690"},{"issue":"8","key":"e_1_2_7_10_1","first-page":"861","article-title":"Comparison of the efficacy of biologics versus conventional systemic therapies in the treatment of psoriasis at a comprehensive psoriasis care center","volume":"12","author":"Au S\u2010C","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljac128"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1256542"},{"key":"e_1_2_7_13_1","unstructured":"Ng'ambiPG.\u2018Quantifying the economic impact of psoriasis\u2019 PhD Thesis.2022https:\/\/research.manchester.ac.uk\/en\/studentTheses\/quantifying\u2010the\u2010economic\u2010impact\u2010of\u2010psoriasis"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.10.016"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hec.4487"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.138"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/0142159X.2020.1755030"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939\u2010023\u201001828\u20103"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2023.04.006"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19031829"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X19864829"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2020.09.004"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010018\u20100279\u20105"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3229032495"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v102.1386"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.24869\/psyd.2017.401"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.508"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010023\u201001060\u20105"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtumed.2021.02.008"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(21)00395\u20103"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.15577"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2023.01.001"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.4236\/oalib.1109989"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2023.115078"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad141"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102022\u2010063902"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2021.03.007"},{"key":"e_1_2_7_38_1","unstructured":"Demographic Census 2022: ethnic\u2010racial identification of the population by sex and age. 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