{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:19:09Z","timestamp":1784542749586,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite advancements in psoriasis treatment, a gap remains in aligning patient satisfaction with clinical outcomes. Our study aimed to evaluate which clinical and psychological factors may impact treatment satisfaction in psoriatic patients undergoing long\u2010term biological therapies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed an observational, cross\u2010sectional, single\u2010center study involving adult patients with moderate\u2010to\u2010severe psoriasis treated with biologics for at least 12\u2009months. We collected sociodemographic characteristics and data on the course of the psoriasis. We also assessed the absolute (residual) Psoriasis Area and Severity Index (PASI), the site of the residual disease, and the severity of pruritus through the Visual Analogue Scale (VAS). Satisfaction was evaluated using the Treatment Satisfaction Questionnaire for Medication (TSQMv.II). The Type D Personality Scale (DS14 questionnaire and Patient Health Questionnaire\u20109 assessed the psychological profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 146 patients were included, and 82.1% were globally satisfied (global satisfaction TSQM score &gt;75). Linear regression analysis showed a negative correlation between global satisfaction scoring and residual PASI. The multivariable analysis found a higher VAS\u2010pruritus score (OR\u2009=\u20091.20, 95% CI\u2009=\u20091.01\u20131.44; <jats:italic>P<\/jats:italic>\u2009=\u20090.043) and not reaching a residual PASI\u2009&lt;\u20092 (OR\u2009=\u20090.30, 95% CI\u2009=\u20090.09\u20130.94, <jats:italic>P<\/jats:italic>\u2009=\u20090.039) as the strongest predictors of global unsatisfied patients (TSQM\u2009&lt;\u200975%).<\/jats:p><jats:p>Other factors unrelated to residual disease, such as gender, class of biologic agent, and type D personality, have also been found to impact patient satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study's findings underscore the complexity of patient satisfaction in psoriasis management and highlight the multifactorial nature of treatment success beyond traditional clinical measures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijd.17509","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T03:29:22Z","timestamp":1728358162000},"page":"531-538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Residual disease is the main, but not the only factor impacting satisfaction in psoriatic patients undergoing biological therapies"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8837-9232","authenticated-orcid":false,"given":"Giacomo","family":"Caldarola","sequence":"first","affiliation":[{"name":"UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche Fondazione Policlinico Universitario A.\u00a0Gemelli \u2013 IRCCS  Rome Italy"},{"name":"Dermatologia, Dipartimento di Medicina e\u00a0Chirurgia Traslazionale Universit\u00e0 Cattolica del Sacro Cuore  Rome 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