{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:43:14Z","timestamp":1783122194069,"version":"3.54.6"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T00:00:00Z","timestamp":1736035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T00:00:00Z","timestamp":1736035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Vulvar Lichen Sclerosus (VLS) is a chronic autoimmune disease that often leads to vulvodynia, a debilitating chronic pain condition in the vulvar region. Treating vulvodynia in the context of VLS presents a significant therapeutic challenge due to the lack of standardized protocols. This article presents a case series of 20 women treated with amitriptyline for vulvodynia secondary to VLS, accompanied by an extended review of the literature. The results suggest that amitriptyline may offer significant pain relief and improvements in the patients\u2019 quality of life, although adverse effects need to be carefully managed. Further studies are needed to validate these findings in larger controlled trials.<\/jats:p>","DOI":"10.1111\/ijd.17634","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T22:53:07Z","timestamp":1736117587000},"page":"725-726","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Amitriptyline for the treatment of vulvodynia in patients with vulvar lichen sclerosus: a case series of 20 patients"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0834-1331","authenticated-orcid":false,"given":"Gaetano","family":"Licata","sequence":"first","affiliation":[{"name":"Dermatology Unit San Antonio Abate Hospital  Trapani Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0278-2443","authenticated-orcid":false,"given":"Eugenia Veronica","family":"Di Brizzi","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania Luigi Vanvitelli  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Tancredi","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania Luigi Vanvitelli  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariachiara","family":"Arisi","sequence":"additional","affiliation":[{"name":"Dermatology Department, ASST Spedali Civili di Brescia University of Brescia  Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6224-5017","authenticated-orcid":false,"given":"Cesare","family":"Ariasi","sequence":"additional","affiliation":[{"name":"Dermatology Department, ASST Spedali Civili di Brescia University of Brescia  Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina Mariarosaria","family":"Giorgio","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania Luigi Vanvitelli  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,5]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2017.1343295"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S191200"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010018\u20100364\u20107"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S448861"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmwh.13456"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.17634","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:57:16Z","timestamp":1773032236000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.17634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,5]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/ijd.17634"],"URL":"https:\/\/doi.org\/10.1111\/ijd.17634","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,5]]},"assertion":[{"value":"2024-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}