{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T16:14:23Z","timestamp":1778861663603,"version":"3.51.4"},"reference-count":5,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 15\u2010year\u2010old female presented with a two\u2010month history of a tender perianal nodule, which was aggravated by sitting or pressure. She denied having any systemic symptoms. Examination revealed a well\u2010defined, erythematous\u2010to\u2010gray nodule measuring 3\u2009\u00d7\u20093\u2009cm, featuring a corrugated surface at the lateral end. Histopathology showed large polygonal cells with abundant granular eosinophilic cytoplasm and small, uniform nuclei. Immunohistochemical staining was strongly positive for S\u2010100 protein and neuron\u2010specific enolase, confirming the diagnosis of a granular cell tumor (GCT). GCT is a rare, usually benign neoplasm of Schwann cell origin, with perianal involvement being extremely uncommon, especially in pediatric patients. Although most cases are asymptomatic, a perianal GCT can cause discomfort and may require surgical excision with sphincter preservation. While malignant transformation is rare, close monitoring is advised. This case highlights the diagnostic challenges of GCT in unusual locations and underscores the importance of histopathology and immunohistochemistry for accurate diagnosis and management.<\/jats:p>","DOI":"10.1111\/ijd.17911","type":"journal-article","created":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T00:59:29Z","timestamp":1749862769000},"page":"1778-1780","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Uncommon Perianal Mass in a Girl: A Diagnostic Challenge"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0391-1860","authenticated-orcid":false,"given":"Sonika","family":"Garg","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nita","family":"Khurana","sequence":"additional","affiliation":[{"name":"Department of Pathology Maulana Azad Medical College  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7135-8494","authenticated-orcid":false,"given":"Vishal","family":"Gaurav","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.9738\/INTSURG-D-13-00149.1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.159642"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjw186"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520982689"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160909500424"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17911","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.17911","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.17911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:40:50Z","timestamp":1778859650000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.17911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,13]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/ijd.17911"],"URL":"https:\/\/doi.org\/10.1111\/ijd.17911","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,13]]},"assertion":[{"value":"2025-02-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}