{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:59:07Z","timestamp":1781240347483,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      The relationship between hidradenitis suppurativa (\n                      <jats:styled-content style=\"fixed-case\">HS)<\/jats:styled-content>\n                      and arthritis is well\u2010established; however, the impact of their combined disease burden and the associated treatment pattern has not been determined yet. This study aimed to assess disease burden and therapeutic approaches in\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      patients with and without arthritis and estimate arthritis prevalence and subtypes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A multicenter, retrospective, case\u2013control study of 272 adults (69 with\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      and arthritis; 203 with\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      only), drawn from a hospital\u2010based cohort of 3644\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      patients across 10 Spanish centers. Controls were matched 1:3 by sex, age, and\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      duration. Statistical analysis included non\u2010parametric tests, logistic regression, and linear mixed\u2010effects models adjusted for confounders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      patients with arthritis had higher rates of immune\u2010mediated diseases, including inflammatory bowel disease (odds ratio [\n                      <jats:styled-content style=\"fixed-case\">OR]<\/jats:styled-content>\n                      9.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and psoriasis (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      2.99,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0038), higher Dermatology Life Quality Index (\n                      <jats:styled-content style=\"fixed-case\">DLQI)<\/jats:styled-content>\n                      scores (6.30 vs. 4.03,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031), more dermatology visits (7.00 vs. 5.00,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0077), and greater biologic therapy use (72.07% vs. 39.90%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). The prevalence of arthritis among\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      patients was 1.70% (95% confidence interval [\n                      <jats:styled-content style=\"fixed-case\">CI]<\/jats:styled-content>\n                      : 1.00%\u20132.70%), with spondyloarthritis being the most common subtype (66.6%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      patients with arthritis have a greater disease burden and higher biologic therapy utilization, emphasizing the need for interdisciplinary care and optimizing resources.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.70125","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T09:09:42Z","timestamp":1761815382000},"page":"774-782","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Disease Burden and Treatment Patterns in Patients With Hidradenitis Suppurativa and Concomitant Arthritis: A Multicenter Case\u2013Control Study"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3325-6785","authenticated-orcid":false,"given":"Patricia","family":"Garbayo\u2010Salmons","sequence":"first","affiliation":[{"name":"Department of Dermatology, Parc Taul\u00ed Hospital Universitari. Institut d'Investigaci\u00f3 i Innovaci\u00f3 Parc Taul\u00ed (I3PT\u2010CERCA) Universitat Aut\u00f2noma de Barcelona  Sabadell Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona (UAB)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6882-2113","authenticated-orcid":false,"given":"Alejandro","family":"Molina\u2010Leyva","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario Virgen de Las Nieves \u2013 Ibs  Granada Spain"},{"name":"Department of Dermatology Universidad de Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Porta\u2010Vilar\u00f3","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Parc Taul\u00ed Hospital Universitari. Institut d'Investigaci\u00f3 i Innovaci\u00f3 Parc Taul\u00ed (I3PT\u2010CERCA) Universitat Aut\u00f2noma de Barcelona  Sabadell Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5040-8483","authenticated-orcid":false,"given":"Alberto","family":"Soto\u2010Moreno","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario Virgen de Las Nieves \u2013 Ibs  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-8152","authenticated-orcid":false,"given":"Rosa","family":"Fornons\u2010Servent","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de Bellvitge  L'Hospitalet de Llobregat 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of Dermatology Hospital del Mar  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9482-1621","authenticated-orcid":false,"given":"J\u00falia","family":"Verdaguer\u2010Faja","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitari Germans Trias i Pujol  Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Mora\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitari Germans Trias i Pujol  Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael S.","family":"Aguayo\u2010Ortiz","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Arnau de Vilanova  Lleida Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Vilarrasa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de la Santa Creu i Sant Pau  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emili","family":"Masferrer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitari M\u00fatua Terrassa  Terrassa Spain"},{"name":"Faculty of Medicine Universitat de Vic\u2010Universitat Central de Catalunya (UVIC\u2010UCC)  Vic Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6001-9120","authenticated-orcid":false,"given":"Oriol","family":"Corral\u2010Maga\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitari M\u00fatua Terrassa  Terrassa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loida","family":"Galvany","sequence":"additional","affiliation":[{"name":"Department of Dermatology Consorci Sanitari Integral  L'Hospitalet de Llobregat 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Spain"},{"name":"Department of Rheumatology, Parc Taul\u00ed Hospital Universitari, Institut d'Investigaci\u00f3 i Innovaci\u00f3 Parc Taul\u00ed (I3PT\u2010CERCA) Universitat Aut\u00f2noma de Barcelona  Sabadell Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Carreras","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Parc Taul\u00ed Hospital Universitari, Institut d'Investigaci\u00f3 i Innovaci\u00f3 Parc Taul\u00ed (I3PT\u2010CERCA) Universitat Aut\u00f2noma de Barcelona  Sabadell Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Feliu\u2010Hern\u00e0ndez","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Parc Taul\u00ed Hospital Universitari, Institut d'Investigaci\u00f3 i Innovaci\u00f3 Parc Taul\u00ed (I3PT\u2010CERCA) Universitat Aut\u00f2noma de Barcelona  Sabadell 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