{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:12:36Z","timestamp":1784542356606,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T00:00:00Z","timestamp":1764460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T00:00:00Z","timestamp":1764460800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100011110","name":"UCB","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011110","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022606","name":"Almirall","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psoriasis is a chronic inflammatory skin and systemic disease with a wide range of clinical manifestations and treatment options, including topicals, phototherapy, non\u2010biologic systemic treatments, and biologics. Understanding regional differences in clinical characteristics and treatment patterns can help improve equity and access to care globally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Global Healthcare Study on Psoriasis (GHSP) is an ongoing multinational, multicenter, longitudinal observational study. This study included cross\u2010sectional data from 1415 patients across Singapore, China, Thailand, the Philippines, and Switzerland, collected between January 2020 and March 2024 using a 48\u2010item questionnaire assessing clinical characteristics, comorbidities, disease severity, quality of life, and treatment patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Plaque psoriasis was the predominant phenotype (90.5%). Mean Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) scores were highest in China and the Philippines. Topical therapy was the most adopted treatment modality in both Asia (79.8%) and Switzerland (96.7%). Phototherapy usage was highest in Switzerland (59.0%) and Singapore (65.4%). Non\u2010biologic systemic agents were more frequently prescribed in Switzerland (64.0%), Singapore (63.2%), and Thailand (84.7%) than in China (20.0%) and the Philippines (29.1%). Methotrexate was the predominant non\u2010biologic except in China, where retinoids predominated. Biologic uptake was highest in Switzerland (59.5%) and Singapore (31.6%) and limited elsewhere by affordability, availability, and preference. Interleukin\u201017A inhibitors were the most prescribed class. Biosimilar use was low (3.0%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our analysis revealed marked disparities in access to biologic treatment and reiterates the need to improve availability and affordability, through greater adoption of biosimilars and enhanced financial support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.70183","type":"journal-article","created":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T08:03:51Z","timestamp":1764489831000},"page":"1195-1202","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Characteristics and Treatment Patterns of Psoriasis in Asia and Switzerland: Results of the Multicentre Global Healthcare Study on Psoriasis (GHSP)"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2871-9051","authenticated-orcid":false,"given":"Eyan","family":"Goh","sequence":"first","affiliation":[{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University  Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1562-8568","authenticated-orcid":false,"given":"Mia\u2010Louise","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9202-0073","authenticated-orcid":false,"given":"Lara V.","family":"Maul","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Zurich  Zurich Switzerland"},{"name":"Faculty of Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes A.","family":"Didaskalu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6625-6445","authenticated-orcid":false,"given":"Leena","family":"Chularojanamontri","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8956-9807","authenticated-orcid":false,"given":"Bryan E. K.","family":"Guevara","sequence":"additional","affiliation":[{"name":"Department of Dermatology Southern Philippines Medical Center  Davao City Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4675-5141","authenticated-orcid":false,"given":"Mei","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Dermatology Skin Disease Prevention and Treatment of Fengxian District of Shanghai  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4565-844X","authenticated-orcid":false,"given":"Min","family":"Zheng","sequence":"additional","affiliation":[{"name":"Dermatology Department Second Affiliated Hospital, Zhejiang University, School of Medicine  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9914-1545","authenticated-orcid":false,"given":"Julia\u2010Tatjana","family":"Maul","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Zurich  Zurich Switzerland"},{"name":"Faculty of Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7607-3124","authenticated-orcid":false,"given":"Hazel H.","family":"Oon","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University  Singapore City Singapore"},{"name":"National Skin Centre and Skin Research Institute of Singapore  Singapore City Singapore"},{"name":"Yong Loo Lin School of Medicine, National University of Singapore  Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.743180"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v104.20329"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljac128"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.15384"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2023.07.857"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2023.07.117"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2023.08.006"},{"key":"e_1_2_11_9_1","unstructured":"World Health Organization \u201cPsoriasis \u201d Sixty\u2010Seventh World Health Assembly 2014 Geneva Switzerland. 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