{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:34:42Z","timestamp":1777948482009,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acquired progressive kinking of the hair (APKH) is an underrecognized hair disorder characterized by a gradual change in hair texture, often manifesting as increased curliness, frizziness, and darkening of the shafts. While various systemic triggers and congenital conditions can induce similar phenotypes, a subset of cases\u2014particularly those involving the frontal and temporal scalp in young males\u2014appears to be linked to androgen\u2010mediated mechanisms. This narrative review focuses on the androgen\u2010dependent phenotype of APKH, integrating clinical, trichoscopic, and histopathological findings and presenting a representative case. We also propose a conceptual framework for distinguishing between androgen\u2010dependent and non\u2013androgen\u2010dependent subtypes. A detailed analysis of all published cases meeting criteria for androgen\u2010sensitive APKH is provided, highlighting patterns of progression, diagnostic clues, and therapeutic implications. Recognizing this presentation as a potential early manifestation of androgenetic alopecia may inform clinical decisions and prompt timely intervention.<\/jats:p>","DOI":"10.1111\/ijd.70281","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T08:16:54Z","timestamp":1768378614000},"page":"974-979","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acquired Progressive Kinking of the Hair: A Narrative Review of the Androgen\u2010Dependent Phenotype"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9807-0546","authenticated-orcid":false,"given":"Eduardo","family":"Corona\u2010Rodarte","sequence":"first","affiliation":[{"name":"Department of Dermatology Instituto Dermatol\u00f3gico de Jalisco \u201cDr Jos\u00e9 Barba Rubio\u201d  Atejamac del Valle Jalisco Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Barrera\u2010Ochoa","sequence":"additional","affiliation":[{"name":"Trichology Clinic, Dermatology Department Hospital General \u201cDr. Manuel Gea Gonz\u00e1lez\u201d  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Mart\u00ednez\u2010Saharopulos","sequence":"additional","affiliation":[{"name":"Private Dermatology Practice, Dermalomas Dermatology and Hair Diseases Center  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marla","family":"Olivas\u2010Altamirano","sequence":"additional","affiliation":[{"name":"Research Unit Medica Sur Clinic and Foundation  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Vargas\u2010Vega","sequence":"additional","affiliation":[{"name":"Research Department Onkimia  Guadalajara Jalisco Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Tosti","sequence":"additional","affiliation":[{"name":"Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery University of Miami Miller School of Medicine  Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Asz\u2010Sigall","sequence":"additional","affiliation":[{"name":"Trichology Clinic, Dermatology Department Hospital General Manuel Gea Gonz\u00e1lez  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1984.tb00766.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1932.01450020107011"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70117-X"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2000.tb02226.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1969.01610260067012"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2023.01.022"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb01135.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1989.01670140104020"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0736-8046.2004.21317.x"},{"issue":"7","key":"e_1_2_10_11_1","first-page":"505","article-title":"Acquired Kinking of the Scalp Hair: A Report of Two Cases, One of Them Associated With Trichiasis","volume":"92","author":"Urbina F. 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