{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:55:52Z","timestamp":1785855352316,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Corticosteroids are frequently used to relieve pruritus or eczematization in scabies, but empirical or prolonged use before diagnosis may modify the disease course.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to examine the impact of corticosteroid exposure (misdiagnosis\u2010related or adjunctive) on clinical severity, mite burden, and healing time, and to assess the initial measurement properties of a novel composite scoring system for standardized severity assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this cross\u2010sectional analytical study, 180 adults (18\u201350\u2009years) with dermoscopically confirmed scabies were classified into three groups: misdiagnosed (steroid\u2010only), standard therapy + steroid, and standard therapy. Severity was assessed using a 0\u20139 composite score integrating pruritus (NRS), mite index, and body surface area involvement (BSA). Internal consistency (Cronbach's\n                      <jats:italic>\u03b1<\/jats:italic>\n                      ) and inter\u2010rater reliability (ICC) were evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both steroid\u2010exposed groups showed significantly higher severity scores (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), longer disease duration (median 8\u2009weeks vs. 3\u2009weeks), and delayed healing compared with standard therapy. Steroid duration correlated with mite index, BSA, and total score (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.005). The scale showed borderline\u2010to\u2010acceptable internal consistency; ICC was good for NRS (0.79) and fair\u2010to\u2010moderate for the total score (0.45).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prior or concurrent corticosteroid exposure increases disease severity and delays recovery in scabies, likely by suppressing local immune responses. The proposed Scabies Severity Scale is a practical, preliminary tool for standardized severity assessment, pending external validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijd.70326","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T09:50:41Z","timestamp":1772963441000},"page":"1856-1863","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Impact of Steroid Use on Scabies Treatment: An\u00a0Evaluation of Clinical Severity, Parasite Burden, and\u00a0the\u00a0Validity of a Novel Scoring System"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8479-5298","authenticated-orcid":false,"given":"Semih","family":"G\u00fcder","sequence":"first","affiliation":[{"name":"Department of Dermatology Bezmialem Vak\u0131f University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1140-9261","authenticated-orcid":false,"given":"\u00d6zlem Su","family":"K\u00fc\u00e7\u00fck","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bezmialem Vak\u0131f University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0745-270X","authenticated-orcid":false,"given":"Didem","family":"Dizman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bezmialem Vak\u0131f University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9170-4262","authenticated-orcid":false,"given":"Sera Nur Y\u00fccesoy","family":"Temiz","sequence":"additional","affiliation":[{"name":"Department of Dermatology Maltepe University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1195-4200","authenticated-orcid":false,"given":"G\u00fcll\u00fc","family":"Gencebay","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bezmialem Vak\u0131f University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5356-6775","authenticated-orcid":false,"given":"Melisa","family":"\u00d6zay","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bezmialem Vak\u0131f University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8604-022X","authenticated-orcid":false,"given":"H\u00fcsna","family":"G\u00fcder","sequence":"additional","affiliation":[{"name":"Department of Dermatology Maltepe University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.17327"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9625936"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17713"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jvc2.25"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2020.58.6.669"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1504a5360"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002387"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llaf107"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00042\u201006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010017\u20102234\u20101"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010017\u20102320\u20104"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.01.010"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0163\u20107258(02)00297\u20108"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.64550\/joid.ejtgm145"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.09.005"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222212365"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2024.09.008"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.11.024"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100625.2008.00786.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12900"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70326","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.70326","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70326","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:35:43Z","timestamp":1785854143000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.70326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,1]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/ijd.70326"],"URL":"https:\/\/doi.org\/10.1111\/ijd.70326","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,1]]},"assertion":[{"value":"2025-11-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}