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Histopathology revealed a granulomatous process, but the etiology remained uncertain despite extensive investigation. This case illustrates the diagnostic challenge of a slowly progressive facial plaque with tuberculoid granulomas and negative microbiological special stains, highlighting the importance of clinicopathological correlation and follow\u2010up in endemic areas for chronic granulomatous dermatoses.<\/jats:p>","DOI":"10.1111\/ijd.70377","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:03:39Z","timestamp":1773029019000},"page":"1587-1589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infiltrated Facial Plaques With 40\u2010Year Evolution"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6993-8940","authenticated-orcid":false,"given":"Andreia Akina","family":"Akamine","sequence":"first","affiliation":[{"name":"Hospital Santa Casa de Curitiba  Curitiba Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7272-9795","authenticated-orcid":false,"given":"Maiara Christine","family":"Macagnan","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Curitiba  Curitiba Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2756-053X","authenticated-orcid":false,"given":"Helena","family":"Zenedin Marchioro","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Curitiba  Curitiba Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2006.05.005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200203050-00004"},{"issue":"2","key":"e_1_2_6_4_1","first-page":"173","article-title":"Cutaneous Tuberculosis: A 20\u2010Year Prospective Study","volume":"15","author":"Kumar B.","year":"2011","journal-title":"International Journal of Tuberculosis and Lung Disease"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2021.07.004"},{"issue":"12","key":"e_1_2_6_6_1","first-page":"939","article-title":"Cutaneous Tuberculosis (Lupus Vulgaris\u2010Type)","volume":"34","author":"Gallo J. 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