{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T16:06:20Z","timestamp":1781107580173,"version":"3.54.1"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Hidradenitis suppurativa (HS) is a disease that impairs the quality of life (QoL), sexual functioning, and fertility of the patients. The relationship between disease characteristics and sexual function remains insufficiently characterized.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The aim of this study is to evaluate the rate of sexual dysfunction among HS patients; and to evaluate its relationship to disease or patient characteristics.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In this multi\u2010centered cross\u2010sectional study, patients were asked to complete a structured online questionnaire including demographics, disease characteristics, the Hidradenitis Suppurativa Self\u2010Assessment Tool (HSSA), HS\u2010specific Dermatology Life Quality Index (HS\u2010DLQI), and validated sexual function instruments (International Index of Erectile Function\u20105 [IIEF\u20105] for males; Female Sexual Function Index [FSFI] for females).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 522 HS patients were included. Higher HSSA stages correlated positively with worse HS\u2010DLQI scores (\n r<\/jats:italic>\n \u2009=\u20090.258,\n p<\/jats:italic>\n \u2009<\u20090.001). Lesions in the head\/neck, inframammary, gluteal, and inguinal regions were associated with greater QoL impairment. Male patients had significantly lower IIEF scores and higher erectile dysfunction (ED) prevalence compared to controls; however, HS was not an independent risk factor for ED in multivariable analysis. Female patients had significantly lower total FSFI scores than controls, particularly in arousal, orgasm, satisfaction, and pain domains, whereas lubrication remained unaffected and desire scores were higher.\n <\/jats:p>\n <\/jats:sec>\n \n Limitations<\/jats:title>\n Recall bias, the self\u2010reported nature of questionnaires, and sociocultural barriers to discussing sexual health may have influenced results.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n HS significantly impairs quality of life, particularly with increasing disease severity and involvement of specific anatomical regions. HS is associated with impaired sexual function in both women and men, with a more pronounced and multifaceted impact observed in female patients. Effective pain and inflammation control may improve sexual outcomes, underscoring the importance of comprehensive, domain\u2010specific assessment in HS management.<\/jats:p>\n \n \n \n image<\/jats:alt-text>\n <\/jats:graphic>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijd.70522","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:48:22Z","timestamp":1781106502000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Hidradenitis Suppurativa on Sexual Function: A Multicentered Cross\u2010Sectional Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4211-2276","authenticated-orcid":false,"given":"Defne","family":"\u00d6zkoca","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology Ko\u00e7 University School of Medicine \u0130stanbul Turkey"},{"name":"Dermatology Clinic Ba\u015fak\u015fehir \u00c7am ve Sakura City Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3857-0848","authenticated-orcid":false,"given":"Hediye","family":"Eker","sequence":"additional","affiliation":[{"name":"Dermatology Clinic Ba\u015fak\u015fehir \u00c7am ve Sakura City Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilay Yerlio\u011flu","family":"Ak","sequence":"additional","affiliation":[{"name":"Dermatology Clinic Ba\u015fak\u015fehir \u00c7am ve Sakura City Hospital \u0130stanbul Turkey"},{"name":"Department of Dermatology and Venerology, \u0130stanbul Faculty of Medicine \u0130stanbul University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beril Kara","family":"Esen","sequence":"additional","affiliation":[{"name":"Department of Public Health Esenler District Health Directorate Istanbul 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