{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T05:54:43Z","timestamp":1791438883349,"version":"4.3.3"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005006","name":"Asan Institute for Life Sciences, Asan Medical Center","doi-asserted-by":"publisher","award":["2025IL0012"],"award-info":[{"award-number":["2025IL0012"]}],"id":[{"id":"10.13039\/501100005006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2026,11]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Subcutaneous panniculitis\u2010like T\u2010cell lymphoma (SPTL) is a rare form of cutaneous lymphoma characterized by neoplastic T\u2010cell infiltration of subcutaneous tissue, clinically mimicking panniculitis. This study aimed to evaluate the applicability and prognostic value of the T component of the Tumor\u2013Node\u2013Metastasis (TNM) classification system, as well as the prognostic significance of skin lesion characteristics in patients with SPTL.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Clinical characteristics and survival outcomes of patients with SPTL treated at a Korean academic medical center were retrospectively reviewed to assess the prognostic significance of TNM T staging and skin lesion features.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Among 43 patients with SPTL, nine had concurrent hemophagocytic lymphohistiocytosis (HLH). Higher T categories were associated with an increased likelihood of HLH. Although overall survival (OS) did not differ significantly across T categories, higher T stage and presence of lipoatrophy correlated with poorer relapse\u2010free survival (RFS). Of all clinical variables, only HLH was significantly associated with reduced OS. Decreased RFS was associated with lipoatrophy, HLH, and visceral or nodal involvement. Multivariable analysis identified T3 stage and HLH as independent prognostic factors of RFS.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Patients with SPTL presenting with extensive skin involvement (T3) have a higher risk of disease relapses and are more likely to develop HLH.<\/jats:p>\n \n \n \n image<\/jats:alt-text>\n <\/jats:graphic>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ijd.70532","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T10:13:31Z","timestamp":1781172811000},"page":"2307-2314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Value of Skin Lesion Characteristics in Subcutaneous Panniculitis\u2010Like T\u2010Cell Lymphoma: A Retrospective Cohort Study Assessing the Applicability of T Category of the\n TNM<\/scp>\n Classification for Primary Cutaneous Lymphomas Other Than Mycosis Fungoides and S\u00e9zary Syndrome"],"prefix":"10.1111","volume":"65","author":[{"given":"Myoung Eun","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-8306","authenticated-orcid":false,"given":"Joon Min","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5263-795X","authenticated-orcid":false,"given":"Soo Hyun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1997-2240","authenticated-orcid":false,"given":"Chong Hyun","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Eun","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0549-464X","authenticated-orcid":false,"given":"Woo Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-881268"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-087288"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5858\/133.2.303"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-010-1936-z"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0251-4"},{"key":"e_1_2_10_7_1","first-page":"1058","article-title":"HAVCR2 Mutations Are Associated With Severe Hemophagocytic Syndrome in Subcutaneous Panniculitis\u2010Like T\u2010Cell Lymphoma","volume":"135","author":"Sonigo 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