{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:18:51Z","timestamp":1783487931278,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A 46\u2010year\u2010old incarcerated man with chronic hepatitis C infection and intravenous drug use presented with a rapidly progressive pruritic eruption involving the scalp, trunk, and limbs, accompanied by patchy scalp alopecia and bilateral panuveitis. Examination demonstrated widespread erythematous papules and plaques with central necrosis, prominent scalp involvement, patchy alopecia, and palmoplantar hyperkeratosis. Skin biopsy revealed epidermal ulceration with dense dermal lymphohistiocytic infiltrate, while immunohistochemistry demonstrated numerous spirochetes and serology revealed a markedly elevated non\u2010treponemal titre. This case of malignant syphilis (\n                    <jats:italic>lues maligna<\/jats:italic>\n                    ) highlights the importance of clinicopathological correlation and consideration of syphilis in the differential diagnosis of ulceronecrotic dermatoses with systemic features.\n                  <\/jats:p>","DOI":"10.1111\/ijd.70575","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:57:39Z","timestamp":1783486659000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46\u2010Year\u2010Old Man"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1750-7934","authenticated-orcid":false,"given":"Alex","family":"Majri","sequence":"first","affiliation":[{"name":"Royal Perth Hospital  Perth Western Australia Australia"},{"name":"The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austen","family":"Anderson","sequence":"additional","affiliation":[{"name":"Royal Perth Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Ng","sequence":"additional","affiliation":[{"name":"Royal Perth Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9477-8291","authenticated-orcid":false,"given":"Nima","family":"Mesbah\u2010Ardakani","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology QEII PathWest Laboratory Medicine WA  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1969.01610190076014"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14248839"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181e8b587"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2021.06.003"},{"key":"e_1_2_9_6_1","unstructured":"CDC \u201cNeurosyphilis Ocular Syphilis and Otosyphilis\u2014STI Treatment Guidelines \u201d(2021) accessed June 12 2026 https:\/\/www.cdc.gov\/std\/treatment\u2010guidelines\/neurosyphilis.htm."}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70575","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.70575","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:57:45Z","timestamp":1783486665000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.70575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,7]]},"references-count":5,"alternative-id":["10.1111\/ijd.70575"],"URL":"https:\/\/doi.org\/10.1111\/ijd.70575","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,7]]},"assertion":[{"value":"2026-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ijd.70575"}}