{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T04:43:32Z","timestamp":1786164212114,"version":"build-2736575974"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Melasma necessitates effective long\u2010term management that goes beyond initial treatment. Although the Kligman\u2013Willis triple combination is the standard induction therapy, prolonged use of corticosteroids raises safety concerns. We propose a maintenance strategy that spares corticosteroids while still utilizing a formulation that has been proven over the years to be the most effective for treating melasma. This approach aims to enhance safety by omitting corticosteroids.<\/jats:p>","DOI":"10.1111\/ijd.70630","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T04:16:17Z","timestamp":1786162577000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rethinking Corticosteroids in the Kligman\u2013Willis Formula for Melasma"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9016-6394","authenticated-orcid":false,"given":"Marina","family":"Landau","sequence":"first","affiliation":[{"name":"Arena Dermatology  Herzliya Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1844-8415","authenticated-orcid":false,"given":"Jane M.","family":"Grant\u2010Kels","sequence":"additional","affiliation":[{"name":"Dermatology Department University of Connecticut School of Medicine  Farmington Connecticut USA"},{"name":"Dermatology Department, College of Medicine University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1780-0824","authenticated-orcid":false,"given":"Fotini","family":"Bageorgou","sequence":"additional","affiliation":[{"name":"For Better Skin Clinic  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8768-4879","authenticated-orcid":false,"given":"Rashmi","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Vardhman Mahavir Medical College and Safdarjung Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0224-7129","authenticated-orcid":false,"given":"Mohamad","family":"Goldust","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Illinois at Chicago, College of Medicine  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,7]]},"reference":[{"issue":"1","key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1001\/archderm.1975.01630130042004","article-title":"A New Formula for Depigmenting Human Skin","volume":"111","author":"Kligman A. 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Review of Management and Treatment Options for Hyperpigmentation","volume":"88","author":"Ko D.","year":"2023","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"4","key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.4103\/2229-5178.142483","article-title":"Side\u2010Effects of Topical Steroids: A Long Overdue Revisit","volume":"5","author":"Coondoo A.","year":"2014","journal-title":"Indian Dermatology Online Journal"},{"issue":"4","key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jaad.2017.01.036","article-title":"Postinflammatory Hyperpigmentation: A Comprehensive Overview: Treatment Options and Prevention","volume":"77","author":"Chaowattanapanit S.","year":"2017","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"7","key":"e_1_2_5_6_1","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1111\/ijd.17718","article-title":"Pathogenesis of Melasma Explained","volume":"64","author":"Ali L.","year":"2025","journal-title":"International Journal of Dermatology"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70630","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.70630","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T04:16:18Z","timestamp":1786162578000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.70630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,7]]},"references-count":5,"alternative-id":["10.1111\/ijd.70630"],"URL":"https:\/\/doi.org\/10.1111\/ijd.70630","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,7]]},"assertion":[{"value":"2026-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ijd.70630"}}