{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:47:33Z","timestamp":1792136853592,"version":"4.4.0"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 78\u2010year\u2010old Chinese woman presented with a one\u2010year history of a progressively enlarging purpuric rash over the central face and nasal dorsum, with subsequent development of a firm midline neck mass. Histopathology revealed dense lymphoplasmacytic infiltrate with fibrosis and obliterative phlebitis. Immunohistochemistry showed over 200 IgG4\u2010positive plasma cells per high\u2010power field with an IgG4\u2010IgG ratio exceeding 40%, and serum IgG4 was markedly elevated at 3648.0\u2009mg\/L, confirming IgG4\u2010related disease (IgG4\u2010RD) with a head\u2010and\u2010neck limited phenotype. She responded well to prednisolone. This case illustrates a rare cutaneous presentation of IgG4\u2010RD, which should be considered in differential diagnoses of head and neck lesions.<\/jats:p>","DOI":"10.1111\/ijd.70700","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:03:11Z","timestamp":1792134191000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>IgG4<\/scp>\n                    \u2010Related Disease Presenting as Inflammatory Midline Pseudotumor of the Face and Neck"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2080-0619","authenticated-orcid":false,"given":"Rowena Lee Ying","family":"Kwan","sequence":"first","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Siong See","family":"Lee","sequence":"additional","affiliation":[{"name":"National Skin Centre  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choon Guan","family":"Chua","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3333-1565","authenticated-orcid":false,"given":"Manish Mahadeorao","family":"Bundele","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiun Yit","family":"Pan","sequence":"additional","affiliation":[{"name":"National Skin Centre  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0b013e3181a5a207"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.72"},{"key":"e_1_2_10_4_1","volume-title":"StatPearls","author":"Nambiar S.","year":"2023"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.08.013"},{"key":"e_1_2_10_6_1","unstructured":"\u201cClinical Phenotypes of IgG4\u2010Related Disease in a Multi\u2010Ethnic Singapore Cohort \u201dACR Meeting Abstracts accessed April 24 2026 https:\/\/acrabstracts.org\/abstract\/clinical\u2010phenotypes\u2010of\u2010igg4\u2010related\u2010disease\u2010in\u2010a\u2010multi\u2010ethnic\u2010singapore\u2010cohort\/."}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijd.70700","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijd.70700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:03:12Z","timestamp":1792134192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijd.70700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,16]]},"references-count":5,"alternative-id":["10.1111\/ijd.70700"],"URL":"https:\/\/doi.org\/10.1111\/ijd.70700","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,16]]},"assertion":[{"value":"2026-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ijd.70700"}}