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However, besides its original purpose, it also provides valuable information about the <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content> polymorphism among Croats. The aim of the present study was to analyse the <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content> allele and haplotype frequencies in a sample of 4000 donors from <jats:styled-content style=\"fixed-case\">CBMDR<\/jats:styled-content>. The distribution of <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010A, HLA\u2010B and HLA\u2010<jats:styled-content style=\"fixed-case\">DRB<\/jats:styled-content>1 alleles did not demonstrate significant differences from the data reported for other European populations. The higher frequency of B*40:02 allele in comparison with B*40:01 and <jats:styled-content style=\"fixed-case\">DRB<\/jats:styled-content>1*11:04 in comparison with <jats:styled-content style=\"fixed-case\">DRB<\/jats:styled-content>1*11:01 is interesting because it represents a difference in comparison with the Western and Northern European populations which are a main source of donors for Croatian patients. The haplotype frequencies show a greater variation and difference in comparison with data from other registries and populations; however, due to a lack of high\u2010resolution haplotype data, comparison was possible only with a very limited number of other populations.<\/jats:p>","DOI":"10.1111\/iji.12117","type":"journal-article","created":{"date-parts":[[2014,4,25]],"date-time":"2014-04-25T06:13:31Z","timestamp":1398406411000},"page":"211-221","source":"Crossref","is-referenced-by-count":33,"title":["<scp>HLA<\/scp>\u2010A, HLA\u2010B and HLA\u2010<scp>DRB<\/scp>1 allele and haplotype diversity among volunteer bone marrow donors from Croatia"],"prefix":"10.1111","volume":"41","author":[{"given":"Z.","family":"Grubic","sequence":"first","affiliation":[{"name":"Tissue Typing Center Clinical Department for Transfusion Medicine and Transplantation Biology University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Burek Kamenaric","sequence":"additional","affiliation":[{"name":"Tissue Typing Center Clinical Department for Transfusion Medicine and Transplantation Biology University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Mikulic","sequence":"additional","affiliation":[{"name":"Croatian Bone Marrow Donor Registry University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Stingl Jankovic","sequence":"additional","affiliation":[{"name":"Tissue Typing Center Clinical Department for Transfusion Medicine and Transplantation Biology University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Maskalan","sequence":"additional","affiliation":[{"name":"Tissue Typing Center Clinical Department for Transfusion Medicine and Transplantation Biology University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Zunec","sequence":"additional","affiliation":[{"name":"Tissue Typing Center Clinical Department for Transfusion Medicine and Transplantation Biology University Hospital Centre Zagreb Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002510050324"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0039.2001.057002118.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0039.2002.600201.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2010.01578.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2161-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0198-8859(00)00138-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2007.05.020"},{"key":"e_1_2_6_9_1","unstructured":"Bone Marrow Worldwide.http:\/\/www.bmdw.org[Accessed on 1 July 2013]."},{"key":"e_1_2_6_10_1","first-page":"263","article-title":"The HLA genetic relationship between a well defined Slovenian population sample and the National haematopoietic stem cell donor registry","volume":"81","author":"Buhler S.","year":"2013","journal-title":"Tissue Antigens"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2007.01.014"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0198-8859(01)00298-1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-223-6_5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2003.12.012"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00164983"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0198-8859(00)00158-0"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1128"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1995.tb02495.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2370.2000.00193.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2008.01033.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/335167a0"},{"key":"e_1_2_6_22_1","volume-title":"HLA 1991. 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