{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T09:11:06Z","timestamp":1696324266756},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,22]],"date-time":"2013-04-22T00:00:00Z","timestamp":1366588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":862,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The schistocytes are fragmented red blood cells mainly observed in the setting of hemolytic anemias where they remain an important criterion for the diagnosis. As the identification of these cells is still problematic, the <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nternational <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ouncil for <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tandardization in <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ematology (<jats:styled-content style=\"fixed-case\">ICSH<\/jats:styled-content>) set up a consensus report in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ovember, 2011. The <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>rench <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ellular <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ematology (<jats:styled-content style=\"fixed-case\">GFHC<\/jats:styled-content>) aimed to collect the opinion of French biologists directly confronted to schistocytes measurements, about these guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among the 578 professionals, 169 (29%) answered to the 10 questions dealing with the identification and measurements of schistocytes as proposed by the <jats:styled-content style=\"fixed-case\">ICSH<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A consensus was reached for the urgent need of such guidelines documents, especially in the current background of the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uropean accreditation <jats:styled-content style=\"fixed-case\">EN ISO<\/jats:styled-content> 15189 rules. A traduction in native (French) language was warmly wished in order to facilitate the diffusion of the information. The pathologic threshold for the diagnosis of thrombotic microangiopathic anemia (<jats:styled-content style=\"fixed-case\">TMA<\/jats:styled-content>) (&gt;1%) remained questionable. For half of the biologists, the new fragmented red blood cell (<jats:styled-content style=\"fixed-case\">FRC<\/jats:styled-content>) parameter recently provided by two manufacturers of automated blood cell counters was still doubtfull for routine use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This survey assessed the impact of international \u2018guidelines\u2019 on the <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>rench biological community. 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