{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:46:29Z","timestamp":1790628389828,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T00:00:00Z","timestamp":1385078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":648,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The presence of schistocytes on the peripheral blood film during disseminated intravascular coagulation (<jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content>) remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined schistocytes count on blood films from 35 <jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content> patients and checked morphological anomalies of all <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty of 35 patients presented with schistocytes and 22 with acanthocytes, which was the commonest shape anomaly. Mean percentage\u00a0\u00b1\u00a0standard deviation was 0.33\u00a0\u00b1\u00a00.38%, median value was 0.1%, and range was 0\u20131.4%. The patients with schistocytes \u2265\u00a01% had circumstances frequently associated with increased schistocytes count (promyelocytic leukaemia, pregnancy, severe infection).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Schistocytes were thus frequently observed in <jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content> patients, usually with low percentage, within or close to the reference range (&lt;0.5%). Schistocytes measurement is not a clue test for the initial diagnosis of <jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content>, but might be of clinical value to suggest an associated or underlying thrombotic microangiopathy if \u2265\u00a01%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijlh.12168","type":"journal-article","created":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T11:04:10Z","timestamp":1385118250000},"page":"439-443","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Schistocytes in disseminated intravascular coagulation"],"prefix":"10.1111","volume":"36","author":[{"given":"J.\u2010F.","family":"Lesesve","sequence":"first","affiliation":[{"name":"Hematology laboratories at Nancy Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Martin","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Nancy Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Banasiak","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Nancy Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Andr\u00e9\u2010Kerne\u00efs","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Meaux Meaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bardet","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Paris Cochin Paris Cochin France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Lusina","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Paris Avicenne Paris Avicenne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kharbach","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Neufchateau Neufchateau France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Genevi\u00e8ve","sequence":"additional","affiliation":[{"name":"Hematology laboratories at Angers hospitals Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Lecompte","sequence":"additional","affiliation":[{"name":"Hematology division Geneva Swizerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-553X.2011.01380.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-553X.2006.00829.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908193410807"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.10450"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200006000-00013"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908193410807"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198307143090217"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2011.10.026"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1254048"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912163412515"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704601"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03721.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701442"}],"container-title":["International Journal of Laboratory Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fijlh.12168","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijlh.12168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:35:52Z","timestamp":1695501352000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijlh.12168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,22]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/ijlh.12168"],"URL":"https:\/\/doi.org\/10.1111\/ijlh.12168","archive":["Portico"],"relation":{},"ISSN":["1751-5521","1751-553X"],"issn-type":[{"value":"1751-5521","type":"print"},{"value":"1751-553X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,22]]},"assertion":[{"value":"2013-11-22","name":"published_online","label":"Published Online","group":{"name":"publication_history","label":"Publication History"}}]}}