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The 2017 WHO classification is not a new edition but an update and revision of the 4th edition. New provisional entities but not new definitive entities are included, and novel molecular data in most of the entities and changes in the nomenclature in few of them have been incorporated. In the context of the mature T\u2010 and NK\u2010cell neoplasms, the most relevant updates concern to: 1\u2014dysregulation of the JAK\/STAT pathway due to gene mutations which are common to various aggressive and indolent neoplasms; 2\u2014incorporation of new molecular players that are relevant to the pathogenesis of these neoplasms and\/or have prognostic implications; 3\u2014inclusion of new provisional entities within the subgroups of anaplastic, primarily intestinal and cutaneous lymphomas such as breast implant\u2010associated anaplastic large cell lymphoma, indolent T\u2010cell lymphoproliferative disorder of the gastrointestinal tract and primary cutaneous acral CD8<jats:sup>+<\/jats:sup> T\u2010cell lymphoma; 4\u2014identification of poor prognostic subtypes of peripheral T\u2010cell lymphomas not otherwise specified (PTCL, NOS) characterized by overexpression of certain genes and of a subgroup PTCL, NOS with a T follicular phenotype that now is included together with angioimmunoblastic T\u2010cell lymphoma under the umbrella of lymphomas with a T follicular helper phenotype; and 5\u2014refinement on the designation and definition of already established entities. A review of the major changes will be outlined.<\/jats:p>","DOI":"10.1111\/ijlh.12817","type":"journal-article","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T10:59:00Z","timestamp":1525863540000},"page":"97-103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["The 2017 WHO update on mature T\u2010 and natural killer (NK) cell neoplasms"],"prefix":"10.1111","volume":"40","author":[{"given":"E.","family":"Matutes","sequence":"first","affiliation":[{"name":"Haematopathology Unit, Hospital Clinic Barcelona University  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,9]]},"reference":[{"key":"e_1_2_16_2_1","volume-title":"WHO classification of tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow SH","year":"2008"},{"key":"e_1_2_16_3_1","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid 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