{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:37:13Z","timestamp":1789925833486,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T00:00:00Z","timestamp":1562198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002468","name":"Dong-A University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002468","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Abbott Alinity hq is a next\u2010generation automated hematology analyzer providing complete blood count (CBC) with 6\u2010part white blood cells (WBC) differential counts. The purpose of this study was to evaluate the performance of the analyzer to verify the diagnostic and clinical utility of the Abbott Alinity hq automated system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated specimen stability, precision, linearity, carry\u2010over, and method comparison to assess the performance of Alinity hq. For comparison of the Alinity hq with Sysmex XN\u20109000, totally 314 samples from adult and pediatric patients including both normal and abnormal hematology profiles were analyzed in parallel. The Alinity hq was also compared with the manual differential counts for the same 314 samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 4\u00b0C, the Alinity hq analyzer showed no significant changes in CBC and WBC differential count up to 48\u00a0hours. When stored at room temperature (18\u201025\u00b0C), all parameters except the mean platelet volume (MPV) were stable up to 36\u00a0hours. The Abbott Alinity hq analyzer demonstrated excellent reproducibility and between\u2010batch precision for all CBC and WBC differential parameters. WBC, red blood cells (RBC), hemoglobin (HGB), and platelets showed good linearity and acceptable carry\u2010over. Comparison with a Sysmex XN\u20109000 analyzer and manual 400\u2010cell differential showed excellent correlation for CBC and WBC differential count parameters (correlation coefficient\u00a0=\u00a00.815\u20100.999) except for mean corpuscular hemoglobin concentration (MCHC) and basophils.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We performed initial validation\u00a0studies and confirmed performance specifications on specimen stability, precision, linearity, carry\u2010over, and method comparison. The Abbott Alinity hq analyzer showed good analytical performance for all standard CBC parameters.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijlh.13082","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T17:25:51Z","timestamp":1562261151000},"page":"657-663","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Performance evaluation of new Abbott Alinity hq hematology analyzer"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3674-8534","authenticated-orcid":false,"given":"Kwang\u2010Sook","family":"Woo","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u2010Hwa","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9738-4204","authenticated-orcid":false,"given":"Gyu\u2010Dae","family":"An","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8307-9820","authenticated-orcid":false,"given":"Hyeon\u2010Ho","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0280-2739","authenticated-orcid":false,"given":"Jin\u2010Yeong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12201"},{"key":"e_1_2_7_3_1","volume-title":"H20\u2013A2: Reference Leukocyte (WBC) Differential Count (Proportional) and Evaluation of Instrumental Methods","author":"Clinical Laboratory Standards Institute","year":"2007"},{"key":"e_1_2_7_4_1","volume-title":"H26\u2013A2: Validation, Verification, and Quality Assurance of Automated Hematology Analyzers","author":"Clinical Laboratory Standards Institute","year":"2010"},{"key":"e_1_2_7_5_1","volume-title":"Abbott Alinity h\u2010series operations manual","year":"2017"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12503"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1532\/LH96.05041"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3343\/kjlm.2007.27.3.162"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-553X.2007.01009.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP1V3UXEIQTSLE"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP7D8ECZRXGWCG"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2018.01.014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12389"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12164"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12903"},{"key":"e_1_2_7_16_1","unstructured":"BullBS AllerR HouwenB.MCHC\u2010red cell index or quality control parameter?in Proceedings of the 26th World Congress of the International Society of Haematology. 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