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There are two models, the original PFA\u2010100 and the contemporary PFA\u2010200. Normal reference ranges (NRRs) provided by the manufacturer are the same for both models, instead being based on the type of test cartridge, for which there are two main ones: collagen\/epinephrine (C\/Epi) and collagen\/adenosine diphosphate (C\/ADP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Comparative evaluations of PFA testing and reporting in six different sites of a large pathology network, aiming to harmonize NRRs and test reporting across all network sites. A separate comparative study of testing a range of samples (<jats:italic>n<\/jats:italic>\u00a0&gt;\u2009150) on a PFA\u2010100 versus that on a PFA\u2010200. Review of contemporary literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Each site was identified to have a different reporting NRR, which after consolidating data permitted establishment of an agreed harmonized NRR for use across the network (C\/Epi: 90\u2013160; C\/ADP: 70\u2013124; based on <jats:italic>n<\/jats:italic>\u00a0&gt;\u2009180). Similarly, each site reported and interpreted results in different ways, and after discussion and consolidation, a harmonized approach to interpretation and reporting was achieved. The separate comparative study of PFA\u2010100 versus PFA\u2010200 testing confirmed instrument equivalence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We achieved harmonized NRRs and reporting for PFA testing across a large pathology network. Our approach may be useful for other laboratory networks wishing to harmonize PFA testing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijlh.13907","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T06:00:15Z","timestamp":1656309615000},"page":"934-944","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Harmonizing platelet function analyzer testing and reporting in a large laboratory network"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2103-1661","authenticated-orcid":false,"given":"Emmanuel J.","family":"Favaloro","sequence":"first","affiliation":[{"name":"Haematology, Institute of Clinical Pathology and Medical Research (ICPMR), NSW Health Pathology, Westmead Hospital  Westmead New South Wales Australia"},{"name":"Sydney Centres for Thrombosis and Haemostasis  Westmead New South Wales Australia"},{"name":"Faculty of Science and Health Charles 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