{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:44:53Z","timestamp":1784763893213,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Ethylenediaminetetraacetic acid (EDTA)\u2010dependent platelet aggregation (PA) can cause medical errors. Currently, there is no reliable method for completely solving this problem. This study aims to solve this problem that has plagued clinical practice for many years by using oscillation method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010one EDTA\u2010PA samples were collected, divided, and disaggregated using the oscillation method at various times and speeds. The samples were analyzed using routine blood tests and blood smears.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Platelet counts (PLT) were increased significantly after oscillation. PLT in the 3000\u2009rpm for 0.5\u2009min group was significantly higher than that in the 500\u2009rpm for 0.5\u2009min group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090. 01). After 3000\u2009rpm oscillation, the PLT gradually increased with time, while compared with the 10\u2010min group, the PLT in the 13\u2010min group showed no significant differences. The effective disaggregation rates in the EDTA\u2010PA samples using the oscillation method and sodium citrate anticoagulant were 96.72% and 65.57%, respectively. There were no significant changes in white blood cell (WBC) or red blood cell (RBC) counts or morphology after the use of the oscillation method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The oscillation method effectively depolymerized EDTA\u2010PA without adverse effects on WBC and RBC. The implementation of this technique promises to resolve the issue of EDTA\u2010PA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijlh.14246","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T10:54:48Z","timestamp":1707303288000},"page":"481-487","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The effect of oscillation depolymerization on ethylenediaminetetraacetic acid\u2010dependent platelet aggregation samples: A cross\u2010over study"],"prefix":"10.1111","volume":"46","author":[{"given":"Dan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Laboratory Diagnostics First Affiliated Hospital of Harbin Medical University  Harbin Heilongjiang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Diagnostics First Affiliated Hospital of Harbin Medical University  Harbin Heilongjiang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.13350"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2007.110"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423\u20100410.1995.tb02542.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.7754\/Clin.Lab.2020.201021"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm\u20102011\u20100892"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1532\/LH96.05019"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102141.1986.tb02962.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102141.1978.tb01089.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830500206"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9213074"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.008522"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102141.2002.03441.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/09537100120071031"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.13920"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.29271\/jcpsp.2022.Supp0.SS146"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/15513815.2021.2021336"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath\u20102012\u2010200930"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9030808"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082515"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301\u20104622(90)88037\u2010s"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm\u20102020\u20101432"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmab090"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12443"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm\u20102012\u20100081"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.13966"}],"container-title":["International Journal of Laboratory Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijlh.14246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T07:36:33Z","timestamp":1715067393000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijlh.14246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,7]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/ijlh.14246"],"URL":"https:\/\/doi.org\/10.1111\/ijlh.14246","archive":["Portico"],"relation":{},"ISSN":["1751-5521","1751-553X"],"issn-type":[{"value":"1751-5521","type":"print"},{"value":"1751-553X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,7]]},"assertion":[{"value":"2023-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}