{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:58:12Z","timestamp":1791233892494,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Hodgkin lymphoma (HL) constitutes 10% of all lymphoma diagnoses and accounts for 5% of lymphoma\u2010related deaths. Accurate prognostication in HL remains crucial, particularly given that 10%\u201320% of patients may receive either insufficient or excessive treatment. This study investigates the effect of hemoglobin, albumin, lymphocyte, and platelet (HALP) score, which is a marker of inflammation status and nutrition, at the time of diagnosis for the patients with HL on prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A total of 147 patients diagnosed with cHL were included in the study, and their data were analyzed retrospectively. The significance of the HALP score and hematological indices [neutrophil\u2010lymphocyte ratio (NLR), lymphocyte\u2010monocyte ratio (LMR), and platelet\u2010lymphocyte ratio (PLR)] as predictors of overall survival (OS) and disease\u2010free survival (DFS) was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients were grouped according to median values for the HALP score and hematological indices. High HALP score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.034), low NLR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033), high LMR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), and low PLR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014) were statistically significant in the early\u2010stage favorable group. DFS and OS were not statistically significant according to the HALP score NLR, LMR, and PLR groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The need for readily applicable, reliable prognostic markers in cHL, where immunotherapy treatments have led to significantly improved survival outcomes, remains persistent.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijlh.14379","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T10:18:33Z","timestamp":1728555513000},"page":"68-78","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prognostic Evaluation of Hemoglobin, Albumin, Lymphocyte, and Platelet (\n                    <scp>HALP<\/scp>\n                    ) Score and Hematological Indices in Classic Hodgkin Lymphoma"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5201-4680","authenticated-orcid":false,"given":"Pusem","family":"Patir","sequence":"first","affiliation":[{"name":"Department of Hematology University of Health Sciences, Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kubra","family":"Cerci","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Health Sciences, Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdal","family":"Kurtoglu","sequence":"additional","affiliation":[{"name":"Department of Hematology University of Health Sciences, Antalya Training and Research Hospital  Antalya 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