{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:29:15Z","timestamp":1790688555438,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T00:00:00Z","timestamp":1763856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T00:00:00Z","timestamp":1763856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Lab Hematology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria\u2010endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8\u2010aminoquinoline drugs used to treat Plasmodium vivax malaria. Increasing access to testing for G6PD deficiency at or near the point of care is critical to expanding the safe treatment of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>P. vivax<\/jats:italic>\n                      <\/jats:styled-content>\n                      malaria. We aimed to evaluate the performance of a semiquantitative test for G6PD deficiency, the SD Biosensor Standard G6PD Test with the Brewer's method, in a reference site for the treatment of infectious diseases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We evaluate the diagnostic accuracy performance of the SD Biosensor Standard G6PD Test in 125 individuals with infectious diseases and other illnesses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Results<\/jats:title>\n                    <jats:p>\n                      We observed a trend of concordance between the G6PD status (Deficient or Normal), with low frequencies of discordances in the screenings. The strength of agreement between G6PD tests was classified as almost perfect in all participants (\n                      <jats:italic>k<\/jats:italic>\n                      \u2009=\u20090.82, 95% CI\u2009=\u20090.66, 0.97) and in sex subgroups: females (\n                      <jats:italic>k<\/jats:italic>\n                      \u2009=\u20090.83, 95% CI\u2009=\u20090.59, 1.00) and males (\n                      <jats:italic>k<\/jats:italic>\n                      \u2009=\u20090.81, 95% CI\u2009=\u20090.59, 1.00). The total concordance percentage (number of concordances\/total) was 95% for females, 97% for males, and 96% overall.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The SD Biosensor STANDARD G6PD test is an innovative point\u2010of\u2010care solution. It offers quantitative measurement of glucose\u20106\u2010phosphate dehydrogenase activity while normalizing for hemoglobin levels. This advancement enables its use in lower\u2010tier clinical and laboratory settings, expanding access to accurate G6PD testing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ijlh.70030","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T05:46:02Z","timestamp":1763963162000},"page":"440-446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the Diagnostic Accuracy of the Quantitative Point\u2010of\u2010Care\n                    <scp>SD<\/scp>\n                    Biosensor Standard\n                    <scp>G6PD<\/scp>\n                    Test for Assessment of\n                    <scp>G6PD<\/scp>\n                    Deficiency in Infectious Diseases"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4564-2141","authenticated-orcid":false,"given":"Flavia Regina Medeiros","family":"da Silva","sequence":"first","affiliation":[{"name":"Hematology and Hemotherapy Service, Evandro Chagas National Institute of Infectious Diseases (INI) Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0004-5084","authenticated-orcid":false,"given":"Alexandre Gomes","family":"Vizzoni","sequence":"additional","affiliation":[{"name":"Hematology and Hemotherapy Service, Evandro Chagas National Institute of Infectious Diseases (INI) Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1936-4774","authenticated-orcid":false,"given":"Daniela","family":"Mendes\u2010de\u2010Almeida","sequence":"additional","affiliation":[{"name":"Hematology and Hemotherapy Service, Evandro Chagas National Institute of Infectious Diseases (INI) Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8420-7321","authenticated-orcid":false,"given":"Joanna","family":"Bokel","sequence":"additional","affiliation":[{"name":"Hematology and Hemotherapy Service, Evandro Chagas National Institute of Infectious Diseases (INI) Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9387-8645","authenticated-orcid":false,"given":"Raquel de Vasconcellos Carvalhaes de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Laboratory Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2208-0294","authenticated-orcid":false,"given":"Andr\u00e9 Machado","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Acute Febrile Illnesses Laboratory Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7340-7044","authenticated-orcid":false,"given":"Yasmine Rangel","family":"Vieira","sequence":"additional","affiliation":[{"name":"Immunobiological Technology Institute, Bio\u2010Manguinhos, Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9899-8547","authenticated-orcid":false,"given":"Simone","family":"da Costa Cruz Silva","sequence":"additional","affiliation":[{"name":"Molecular Diagnosis and Cytometry Service Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,23]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60073-2"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019000944"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.43154"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475\u20102875\u20109\u2010115"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010016\u20101335\u20101"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001339"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/0074\u20100276140123"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.16366"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003084"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009649"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20105573\u20108\u20101"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516\u201084842007000400011"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010021\u201003803\u20101"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.18\u20100612"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196716"},{"key":"e_1_2_13_17_1","unstructured":"World 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