{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:13:59Z","timestamp":1771046039708,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01 ES021724"],"award-info":[{"award-number":["R01 ES021724"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG016592"],"award-info":[{"award-number":["R01 AG016592"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG041200"],"award-info":[{"award-number":["R01 AG041200"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obese adults have a higher risk of obstructive sleep apnoea (OSA); however, the relationship between childhood obesity and adult OSA risk is unclear.<\/jats:p><jats:p>Objectives<\/jats:p><jats:p>This study aimed to examine overweight\/obesity (OW) in childhood and risk of OSA in middle age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Childhood OW status was classified as never OW, weight cycling, persistent OW and incident OW. After 35\u2009years of follow\u2010up, high risk for OSA was determined by a positive score in \u22652 domains on the Berlin Questionnaire with obesity removed from scoring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At initial assessment, mean (SD) age was 9.9 (2.9) years, and 23.9% were OW. Overall, 25.7% had scores indicating a high risk for OSA. Compared with participants who were never OW, those with persistent OW and incident OW were 1.36 (95%CI: 1.04\u20131.77) and 1.47 (1.11\u20131.96) times more likely to be high risk for OSA, after adjustment for multiple risk factors and adult OW status. Participants with an OW duration of 1\u20134\u2009years, 5\u20138\u2009years, and 8+\u2009years were 0.96 (0.44\u20132.09), 1.20 (0.70\u20132.04) and 1.52 (1.22\u20131.90) times more likely to be high risk for OSA compared with those who were never OW (<jats:italic>P<\/jats:italic> for trend: 0.0002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that childhood OW is associated with a high risk of OSA in middle age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijpo.12103","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T08:56:45Z","timestamp":1453193805000},"page":"535-542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Childhood obesity patterns and relation to middle\u2010age sleep apnoea risk: the Bogalusa Heart Study"],"prefix":"10.1111","volume":"11","author":[{"given":"L. A.","family":"Bazzano","sequence":"first","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Bertisch","sequence":"additional","affiliation":[{"name":"Department of Medicine Beth Israel Deaconess Medical Center  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Yao","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Community Health University of Minnesota  Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. W.","family":"Harville","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Gustat","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. S.","family":"Webber","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Tulane University School of Public Health and Tropical Medicine  New Orleans LA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Redline","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders Department of Medicine Brigham and Women's Hospital  Boston MA USA"},{"name":"Department of Neurology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws342"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61622-0"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27662"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.189420"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.5.9809079"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.732"},{"key":"e_1_2_9_8_1","volume-title":"Health, United States, 2011: With Special Features on Socioeconomic Status and Health","author":"National Center for Health Statistics (US)","year":"2012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.S2.518"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2047-6310.2011.00046.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2010.222"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27649"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-007-0132-z"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2185"},{"key":"e_1_2_9_15_1","volume-title":"Cardiovascular Risk Factors in Children \u2013 The Early Natural History of Atherosclerosis and Essential Hypertension","author":"Berenson GS","year":"1980"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-131-7-199910050-00002"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.07.043497"},{"key":"e_1_2_9_18_1","unstructured":"World Health Organization (WHO).Multicentre Growth Reference Study Group. 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