{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:29:54Z","timestamp":1784762994215,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T00:00:00Z","timestamp":1572912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["T32HL098048"],"award-info":[{"award-number":["T32HL098048"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HD034569"],"award-info":[{"award-number":["R01HD034569"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UH3OD023286"],"award-info":[{"award-number":["UH3OD023286"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine associations of hair cortisol concentration (HCC) in mid\u2010childhood and change in HCC from mid\u2010childhood to early adolescence (\u0394HCC) with early adolescent adiposity and cardiometabolic biomarker measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In Project Viva, a pre\u2010birth cohort of mothers and children, we measured HCC in 599 white children in mid\u2010childhood and in 426 of these participants in early adolescence. We used multivariable linear regression to examine associations of mid\u2010childhood HCC and \u0394HCC with BMI\u2010for\u2010age\u2010and\u2010sex <jats:italic>z<\/jats:italic> score, waist circumference, waist\u2010height ratio, dual X\u2010ray absorptiometry total and trunk fat mass, a metabolic risk <jats:italic>z<\/jats:italic> score, adiponectin, HOMA\u2010IR, high\u2010density lipoprotein, C\u2010reactive protein, interleukin\u20106, leptin, and systolic blood pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over a mean (SD) follow\u2010up of 5.2 (0.8) years, we did not find associations of mid\u2010childhood HCC with BMI\u2010for\u2010age\u2010and\u2010sex <jats:italic>z<\/jats:italic> score (<jats:italic>\u03b2<\/jats:italic> = 0.00 per 1\u2010interquartile range of HCC, 95% confidence interval [CI], \u22120.08 to 0.07), waist circumference (<jats:italic>\u03b2<\/jats:italic> = \u22120.04 cm, 95% CI, \u22120.83 to 0.74), metabolic risk <jats:italic>z<\/jats:italic> score (<jats:italic>\u03b2<\/jats:italic> = 0.04, 95% CI, \u22120.03 to 0.11), or other cardiometabolic measures except for an increase in log\u2010transformed HOMA\u2010IR (<jats:italic>\u03b2<\/jats:italic> = 0.10, 95% CI, 0.04\u20100.17). \u0394HCC was not associated with any outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found that mid\u2010childhood HCC was not associated with early adolescent adiposity or cardiometabolic biomarkers except for a slight increase in HOMA\u2010IR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijpo.12592","type":"journal-article","created":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T15:58:26Z","timestamp":1572969506000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Childhood hair cortisol concentration and early teen cardiometabolic outcomes"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3025-5931","authenticated-orcid":false,"given":"Joshua","family":"Petimar","sequence":"first","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts"},{"name":"Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheryl L.","family":"Rifas\u2010Shiman","sequence":"additional","affiliation":[{"name":"Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010France","family":"Hivert","sequence":"additional","affiliation":[{"name":"Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute  Boston Massachusetts"},{"name":"Diabetes Unit Massachusetts General Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abby F.","family":"Fleisch","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetes Maine Medical Center  Portland Maine"},{"name":"Center for Outcomes Research and Evaluation Maine Medical Center Research Institute  Portland Maine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Tiemeier","sequence":"additional","affiliation":[{"name":"Department of Social and Behavioral Sciences Harvard T.H. Chan School of Public Health  Boston Massachusetts"},{"name":"Department of Child and Adolescent Psychiatry Erasmus Medical Center\u2010Sophia Children's Hospital  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Oken","sequence":"additional","affiliation":[{"name":"Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute  Boston Massachusetts"},{"name":"Department of Nutrition Harvard, T.H. Chan School of Public Health  Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2009.184291"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-3797(98)00017-8"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22155"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.130.3.355"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0960513"},{"key":"e_1_2_8_7_1","article-title":"Salivary cortisol does not correlate with metabolic syndrome markers or subjective stress in overweight children","volume":"3","author":"Strait RB","year":"2018","journal-title":"Journal of Childhood Obesity"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-4398"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2013.09.006"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2008.08.024"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04350.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2013.03.008"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(99)00146-2"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.109.1.45"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-4085"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-3-6"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2307\/1130220"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01537962"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2016.113"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2013.10.005"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000079841"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163639"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.11.008"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2019.04.028"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.12.017"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2017.10.022"}],"container-title":["Pediatric Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijpo.12592","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ijpo.12592","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ijpo.12592","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T01:31:47Z","timestamp":1694136707000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ijpo.12592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,5]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/ijpo.12592"],"URL":"https:\/\/doi.org\/10.1111\/ijpo.12592","archive":["Portico"],"relation":{},"ISSN":["2047-6302","2047-6310"],"issn-type":[{"value":"2047-6302","type":"print"},{"value":"2047-6310","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,5]]},"assertion":[{"value":"2019-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12592"}}