{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T17:49:32Z","timestamp":1759600172413,"version":"3.41.2"},"reference-count":46,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["242187"],"award-info":[{"award-number":["242187"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["200310013"],"award-info":[{"award-number":["200310013"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Obesity"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the importance of time in pregnancy and neonatal sex on the association between maternal metabolic parameters and neonatal sum of skinfolds.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a longitudinal, secondary analysis of the vitamin D and lifestyle intervention for gestational diabetes mellitus study, conducted in nine European countries during 2012 to 2015. Pregnant women with a pre\u2010pregnancy body mass index (BMI) of \u226529\u2009kg\/m<jats:sup>2<\/jats:sup> were invited to participate. We measured 14 maternal metabolic parameters at three times during pregnancy: &lt;20\u2009weeks, 24 to 28\u2009weeks, and 35 to 37\u2009weeks of gestation. The sum of four skinfolds assessed within 2\u2009days after birth was the measure of neonatal adiposity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 458 mother\u2010infant pairs (50.2% female infants) were included. Insulin resistance (fasting insulin and HOMA\u2010index of insulin resistance) in early pregnancy was an important predictor for boys' sum of skinfolds, in addition to fasting glucose and maternal adiposity (leptin, BMI and neck circumference) throughout pregnancy. In girls, maternal lipids (triglycerides and fatty acids) in the first half of pregnancy were important predictors of sum of skinfolds, as well as fasting glucose in the second half of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Associations between maternal metabolic parameters and neonatal adiposity vary between different periods during pregnancy. This time\u2010dependency is different between sexes, suggesting different growth strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ijpo.12628","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T11:40:48Z","timestamp":1583494848000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Temporal relationships between maternal metabolic parameters with neonatal adiposity in women with obesity differ by neonatal sex: Secondary analysis of the DALI study"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7778-2616","authenticated-orcid":false,"given":"Rodrigo A.","family":"Lima","sequence":"first","affiliation":[{"name":"Institute of Sport Science University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gernot","family":"Desoye","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medizinische Universitaet Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Simmons","sequence":"additional","affiliation":[{"name":"Western Sydney University  Campbelltown New South Wales Australia"},{"name":"The Institute of Metabolic Science Addenbrooke's Hospital  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Devlieger","sequence":"additional","affiliation":[{"name":"KU Leuven Department of Development and Regeneration: Pregnancy, Fetus and Neonate, Gynaecology and Obstetrics University Hospitals Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4254-6664","authenticated-orcid":false,"given":"Sander","family":"Galjaard","sequence":"additional","affiliation":[{"name":"KU Leuven Department of Development and Regeneration: Pregnancy, Fetus and Neonate, Gynaecology and Obstetrics University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC University Medical Centre  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Corcoy","sequence":"additional","affiliation":[{"name":"Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M.","family":"Adelantado","sequence":"additional","affiliation":[{"name":"Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau  Barcelona Spain"},{"name":"CIBER Bioengineering, Biomaterials and Nanotechnology Instituto de Salud Carlos III  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fidelma","family":"Dunne","sequence":"additional","affiliation":[{"name":"Galway Diabetes Research Centre and College of Medicine Nursing and Health Sciences National University of Ireland  Galway Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Harreiter","sequence":"additional","affiliation":[{"name":"Gender Medicine Unit, Endocrinology and Metabolism, Department of Internal Medicine III Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Kautzky\u2010Willer","sequence":"additional","affiliation":[{"name":"Gender Medicine Unit, Endocrinology and Metabolism, Department of Internal Medicine III Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Damm","sequence":"additional","affiliation":[{"name":"Center for Pregnant Women with Diabetes, Department of Endocrinology and Obstetrics, Rigshospitalet Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth R.","family":"Mathiesen","sequence":"additional","affiliation":[{"name":"Center for Pregnant Women with Diabetes, Department of Endocrinology and Obstetrics, Rigshospitalet Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorte M.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Odense Odense University Hospital  Odense Denmark"},{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"},{"name":"Department of Clinical Research, Faculty of Health Sciences University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lise\u2010Lotte","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"},{"name":"Department of Clinical Research, Faculty of Health Sciences University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mette","family":"Tanvig","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"},{"name":"Department of Clinical Research, Faculty of Health Sciences University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annunziata","family":"Lapolla","sequence":"additional","affiliation":[{"name":"Universita Degli Studi di Padova  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria G.","family":"Dalfra","sequence":"additional","affiliation":[{"name":"Universita Degli Studi di Padova  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Bertolotto","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliero Universitaria \u2013 Pisa  Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Wender\u2010Ozegowska","sequence":"additional","affiliation":[{"name":"Medical Faculty I Poznan University of Medical Sciences  Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Zawiejska","sequence":"additional","affiliation":[{"name":"Medical Faculty I Poznan University of Medical Sciences  Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Hill","sequence":"additional","affiliation":[{"name":"Recherche en Sant\u00e9 Lawson SA  Bronschhofen Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank J.","family":"Snoek","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith G. 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